Managing scarlet fever

Bulletin, Drug and Therapeutics

doi:10.1136/bmj.k3005

Cited by 5 publications

(5 citation statements)

References 9 publications

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“…É considerado um diagnóstico diferencial importante. 15 O escore de Egami é um modelo preditor de resistência à IGEV, desenvolvido numa população de pacientes japoneses em 2006, com N de 320 indivíduos, com sensibilidade de 78% e especificidade de 76%. 11 Sobre a aplicação desse escore no estudo, no grupo de pacientes refratários, apenas dois pacientes apresentaram pontuação para alto risco (pontuação ≥ 3), equivalendo a minoria da amostra (1,14 ± 1,231).…”

Section: Resultsunclassified

Refratariedade ao tratamento da Doença de Kawasaki com imunoglobulina endovenosa: uma análise retrospectiva

Melo

Magalhães²,

Gomes

et al. 2020

Com. Ciências Saúde

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O objetivo do estudo consiste em analisar os fatores que influenciaram a refratariedade ao tratamento da doença de Kawasaki com imunoglobulina endovenosa no serviço de reumatologia pediátrica do Hospital da Criança de Brasília José Alencar. A pesquisa é retrospectiva (caso-controle) e comparativa (refratários x responsivos). Foram avaliados dados epidemiológicos, clínicos e laboratoriais, sendo a única variável com relevância estatística (p= 0,006) o maior nível de plaquetas em refratários, podendo sugerir maior risco de complicações como formação de trombos. A predição de risco a refratariedade continua um desafio, necessitando de abordagem direcionada à população brasileira.

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Section: Resultsunclassified

Refratariedade ao tratamento da Doença de Kawasaki com imunoglobulina endovenosa: uma análise retrospectiva

Melo

Magalhães²,

Gomes

et al. 2020

Com. Ciências Saúde

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“…The preferred treatment of scarlet fever is beta lactam antibiotics, penicillin V, or amoxicillin for 10 days, due to their approved cost effectiveness. Other options, if a patient is allergic to penicillin, include macrolides and cephalosporins [8].…”

Section: Case Presentationmentioning

confidence: 99%

Atypical Presentation of Scarlet Fever

Alotaibi¹,

Binsaqr²,

Mutlaq³

et al. 2022

Cureus

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Scarlet fever is an infectious illness, which is caused by Streptococcus pyogenes. It causes exanthema and a characteristic tonsillopharyngitis. Its diagnosis is typically straightforward. However, due to the diverse clinical presentation of scarlet fever, one has to be cautious about atypical rash distribution that might go unrecognized or be misdiagnosed. Despite the fact that scarlet fever is primarily a pediatric illness, it can affect people of any age group. The case presented describes the clinical difficulty in the diagnosis of scarlet fever in an adult patient with atypical rash distribution involving dorsum of the hand and feet only till the level of wrists and ankles joints. A high degree of suspicion is required to diagnose this rare presentation and early treatment is essential to limit the spread of the disease.

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“…Emm, the gene encoding M protein, is the basis for sequence typing that used to differentiate strain serotype. Emm typing is based on sequence diversity of the 5′ region of emm (6)(7)(8)(9). Sequence diversity of M protein has generated over 260 different emm types currently reported in the database from US CDC.…”

Section: Introductionmentioning

confidence: 99%

Emm type distribution of group A Streptococcus in China during 1990 and 2020: a systematic review and implications for vaccine coverage

Xiang

Zhang

Zhao

et al. 2023

Front. Public Health

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BackgroundThe recent increase of group A Streptococcus (GAS) infections in Europe has aroused global concern. We aim to provide molecular biological data for GAS prevention and control in China by analyzing the temporal shift of emm type.MethodsWe collected studies reporting GAS emm types in China from 1990 to 2020 by PRISMA statement and established a summary database including emm types and literature quality assessment. Based on the database we analyzed the geographic distribution of emm types from 1990 to 2020 and assessed the coverage of the known GAS 30-valent vaccine. Outbreak-associated emm types that had been reported over the past 30 years were also included.Results47 high quality studies were included for a systematic analysis of emm type distribution. This generated a database including totally 12,347 GAS isolates and 85 emm types. Shift of dominant emm type was witnessed during the past 30 years in China. In mainland China, dominant types changed from emm3, emm1, emm4, emm12 in 1990s to emm12 and emm1 in 2000s and 2010s. Hong Kong and Taiwan were dominated by emm12, emm4 and emm1, of which emm4 reduced but emm12 increased in 2010s significantly. From 1990 to 2020, newly found emm types were increasingly reported in various regions of China. The reported 30-valent M protein vaccine covered 26 M types prevalent in China, including all dominant types.

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Managing scarlet fever

Cited by 5 publications

References 9 publications

Refratariedade ao tratamento da Doença de Kawasaki com imunoglobulina endovenosa: uma análise retrospectiva

Refratariedade ao tratamento da Doença de Kawasaki com imunoglobulina endovenosa: uma análise retrospectiva

Atypical Presentation of Scarlet Fever

Emm type distribution of group A Streptococcus in China during 1990 and 2020: a systematic review and implications for vaccine coverage

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