Managing prenatally diagnosed asymptomatic congenital cystic adenomatoid malformation

Abstract

Our data suggest that patients with PDA-CCAM may be observed safely until they become symptomatic or changes in size are observed radiologically.

Prediction of Pediatric Outcome after Prenatal Diagnosis and Expectant Antenatal Management of Congenital Cystic Adenomatoid Malformation

“…The prevalence of the composite adverse postnatal outcome was 15%, and so the majority of infants (85%) had an uncomplicated course. Similarly, other studies of postnatal follow-up after prenatal diagnosis of CCAM have also reported good outcomes [7,11,15,16,17,18,19,20,21,22,23]. Although the prevalence of asthma in our cohort is similar to estimates in the general population [24], children with the composite adverse postnatal outcome were more likely to have asthma.…”

“…When we repeated the association between the CVR and composite adverse postnatal outcome only for those cases where the CVR was calculated in the second or early third trimester (<28 weeks) (n = 47), it was still statistically significant (Mann-Whitney test, z = 2.52, p = 0.01). On the other hand, the study’s strengths include a sample size that is larger than other postnatal follow-up studies of CCAM and a median age of follow-up comparable to these other studies [7,11,15,16,17,18,19,20,21,22,23]. …”

Does thoracoscopy have advantages over open surgery for asymptomatic congenital lung malformations? An analysis of 1626 resections

“…A further two independent reviewers assessed the quality of all included articles using the Rangel scoring system, a validated quality assessment scale (published in 2003) for assessing retrospective pediatric surgical case series. [13] The mean of these scores was used to rank articles as 'poor' (0-15), 'fair' (16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30) or 'good' (31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44)(45) Having undertaken data collection it became apparent that the majority of studies available did not include a measure of variance in the publication. When the measure of interest is a frequency, for example, when looking at the number of complications, it is possible to compute an estimate of the variance of the measure of interest such as the risk ratio from the frequency data.…”

Congenital cystoid adenomatoid malformation: Surgery in a young child

“…2 Congenital diaphragmatic hernia is a common differential on chest radiography. The clinical course depends on whether CCAM is symptomatic or asymptomatic at birth, with the latter being more common.…”