Managing obesity through natural polyphenols: A review

Singh, M. P.; Thrimawithana, Thilini; Shukla, Ravi; Adhikari, Benu

doi:10.1016/j.fufo.2020.100002

Cited by 54 publications

(32 citation statements)

References 148 publications

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“…You et al, (2018) and Singh et al, (2020) found that brown rice bran extract has the potential to inhibit pancreatic lipase. 17 Inhibition of fat absorption is the main modulator responsible for reducing triglycerides.…”

Section: Resultsmentioning

confidence: 99%

Oral Administration of Red Rice (Oryza nivara) Bran Extract Reduced Weight, Visceral Fat And Liver Steatosis Amount in Obesity Male Wistar Rats (Rattus norvegicus)

Puspitasari

Pangkahila

Dewi

2021

nsmc

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Background: Nonalcoholic fatty liver disease (NAFLD) is associated with obesity. Red rice (Oryza nivara) bran is known to contain polyphenol and antioxidants that might be potential in reducing body weight and visceral fat in obese mice and preventing liver steatosis. This study was aimed to prove the effect of oral administration of red rice bran (Oryza nivara) extract on body weight, visceral fat, and liver steatosis amount in obese male Wistar rats. Method: In this research, the subjects were 36 male obese (Lee index > 0.3) white rats (Rattus norvegicus) Wistar strain, 4-5 months old, divided into two groups. The control group received a placebo and the treatment group received 460mg/200gram red rice bran extract for 5-weeks. Bodyweight, visceral fat, and the amount of liver steatosis were observed. Differences between groups in each variable were analyzed. Results: The weight of the control group and the treatment group was 321.17 ± 19.04 grams and 305.72 ± 12.89 grams (p < 0.05). The visceral fat weight was 3.15 ± 0.34 grams in the control group and 2.99 ± 0.34 grams (p > 0.05) in the treatment group. Liver steatosis amount was 41 ± 18 cells per visual field in the control group, and 21 ± 12 (p < 0.05) in the treatment group. Conclusion: Oral administration of red rice bran extract can reduce body weight and liver steatosis amount in obese Wistar rats. The extract of red rice bran did not have a significant effect in reducing visceral fat.

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Section: Resultsmentioning

confidence: 99%

Oral Administration of Red Rice (Oryza nivara) Bran Extract Reduced Weight, Visceral Fat And Liver Steatosis Amount in Obesity Male Wistar Rats (Rattus norvegicus)

Puspitasari

Pangkahila

Dewi

2021

nsmc

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“…It has been found that luteolin, which is a Chinese herb, may be putative Furin inhibitor with tremendous benefits against Dengue Fever, and application of Chinese herbals and ion channel inhibitors can restrict the endothelial penetration of SARS-CoV-2 [98]. Natural phenolic compounds can be beneficially applied as food or fortified foods to control obesity [99].…”

Section: Medicinal Plants and Obesitymentioning

confidence: 99%

Natural Dietary and Medicinal Plants with Anti-Obesity Therapeutics Activities for Treatment and Prevention of Obesity during Lock Down and in Post-COVID-19 Era

2021

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Overweight and obesity have become global epidemics, especially during the lockdown due to the COVID-19 pandemic. The potential of medicinal plants as a better and safe option in treating obesity and overweight has gained attention in recent years. Obesity and overweight has become a major public health concern, and its incidence rising at an alarming rate. Obesity is one of the major types of metabolic syndrome, resulting in various types of problems such as hypertension, diabetes, dyslipidemia, and excess fat accumulation. The current searching was done by the keywords in main indexing systems including Scopus, PubMed/MEDLINE, the search engine of Google Scholar, and Institute for Scientific Web of Science. The keywords were traditional medicine, health benefits, pharmaceutical science, pomegranate, punicalin, punicalagin, and ellagitannins. Google Scholar was searched manually for possible missing manuscripts, and there was no language restriction in the search. This review was carried out to highlight the importance of medicinal plants which are common in traditional medicinal sciences of different countries, especially Asia to prevent and treatment of obesity and overweight during the global pandemic and the post-COVID-19 era.

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“…If before they were considered xenobiotics with the ability to reduce the absorption of proteins and other bioactive compounds, today, their presence in food is increasingly important, as many depth studies have shown their ability to counteract oxidative stress, and therefore, preventing, or attenuating the symptoms of many chronic diseases, such as diabetes and cardiovascular pathologies, and also to control weight [ 24 , 25 ]. These compounds already showed ability to regulate the appetite and lipid metabolism, inhibit the differentiation of adipocytes and serve as beneficial gut microbiota prebiotics [ 26 ]. Furthermore, they are able to reduce the activity of disaccharidases (i.e., α -glucosidase and α -amylase) and the absorption of sugars, and improve the use of monosaccharides by muscle cells [ 27 ].…”

Section: Phenolic Compounds In Human Healthmentioning

confidence: 99%

Consumption of Phenolic-Rich Food and Dietary Supplements as a Key Tool in SARS-CoV-19 Infection

Flores-Félix

Gonçalves

Alves

et al. 2021

Foods

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The first cases of COVID-19, which is caused by the SARS-CoV-2, were reported in December 2019. The vertiginous worldwide expansion of SARS-CoV-2 caused the collapse of health systems in several countries due to the high severity of the COVID-19. In addition to the vaccines, the search for active compounds capable of preventing and/or fighting the infection has been the main direction of research. Since the beginning of this pandemic, some evidence has highlighted the importance of a phenolic-rich diet as a strategy to reduce the progression of this disease, including the severity of the symptoms. Some of these compounds (e.g., curcumin, gallic acid or quercetin) already showed capacity to limit the infection of viruses by inhibiting entry into the cell through its binding to protein Spike, regulating the expression of angiotensin-converting enzyme 2, disrupting the replication in cells by inhibition of viral proteases, and/or suppressing and modulating the host’s immune response. Therefore, this review intends to discuss the most recent findings on the potential of phenolics to prevent SARS-CoV-2.

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Managing obesity through natural polyphenols: A review

Cited by 54 publications

References 148 publications

Oral Administration of Red Rice (Oryza nivara) Bran Extract Reduced Weight, Visceral Fat And Liver Steatosis Amount in Obesity Male Wistar Rats (Rattus norvegicus)

Oral Administration of Red Rice (Oryza nivara) Bran Extract Reduced Weight, Visceral Fat And Liver Steatosis Amount in Obesity Male Wistar Rats (Rattus norvegicus)

Natural Dietary and Medicinal Plants with Anti-Obesity Therapeutics Activities for Treatment and Prevention of Obesity during Lock Down and in Post-COVID-19 Era

Consumption of Phenolic-Rich Food and Dietary Supplements as a Key Tool in SARS-CoV-19 Infection

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