Management of unspecified anxiety disorder: Expert consensus

Sakurai, Hitoshi; Inada, Keiichi; Aoki, Yumi; Takeshima, Masahiro; Ie, Kenya; Kise, Morito; Yoshida, Eriko; Tsuboi, Takashi; Hori, Hikaru; Inada, Yasushi; Shimizu, Eiji; Mishima, Kazuo; Watanabe, Koichiro; Takaesu, Yoshikazu

doi:10.1002/npr2.12323

Cited by 3 publications

(3 citation statements)

References 22 publications

(47 reference statements)

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“…Our findings indicate that primary care physicians exercise caution when prescribing benzodiazepine anxiolytic drugs and resort to alternative management strategies, including fundamental nonpharmacological interventions, to some extent for this condition. This is consistent with expert consensus that benzodiazepine anxiolytics are not recommended as first‐line treatment for unspecified anxiety disorder 15 …”

Section: Discussionsupporting

confidence: 87%

“…This is consistent with expert consensus that benzodiazepine anxiolytics are not recommended as first-line treatment for unspecified anxiety disorder. 15 Despite the familiarity, benzodiazepine anxiolytics were not highly prioritized as primary treatment for unspecified anxiety disorder. There was no consistent pattern observed in the duration of action among the familiar and relatively prescribed benzodiazepine anxiolytics for primary treatment.…”

Section: Discussionmentioning

confidence: 99%

“…This is consistent with expert consensus that benzodiazepine anxiolytics are not recommended as first‐line treatment for unspecified anxiety disorder. 15 …”

Section: Discussionmentioning

confidence: 99%

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Clinical practice for unspecified anxiety disorder in primary care

Sakurai

Takeshima

Inada³

et al. 2023

PCN Reports

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AimClinicians face difficulties in making treatment decisions for unspecified anxiety disorder due to the absence of any treatment guidelines. The objective of this study was to investigate how familiar and how often primary care physicians use pharmacological and nonpharmacological approaches to manage the disorder.MethodsA survey was conducted among 117 primary care physicians in Japan who were asked to assess the familiarity of using each treatment option for unspecified anxiety disorder on a binary response scale (0 = “unfamiliar,” 1 = “familiar”) and the frequency on a nine‐point Likert scale (1 = “never used,” 9 = “frequently used”).ResultsWhile several benzodiazepine anxiolytics were familiar to primary care physicians, the frequencies of prescribing them, including alprazolam (4.6 ± 2.6), ethyl loflazepate (3.6 ± 2.4), and clotiazepam (3.5 ± 2.3), were low. In contrast, certain nonpharmacological options, including lifestyle changes (5.4 ± 2.3), coping strategies (5.1 ± 2.7), and psychoeducation for anxiety (5.1 ± 2.7), were more commonly utilized, but to a modest extent. When a benzodiazepine anxiolytic drug failed to be effective, primary care physicians selected the following management strategies to a relatively high degree: differential diagnosis (6.4 ± 2.4), referral to a specialist hospital (5.9 ± 2.5), lifestyle changes (5.2 ± 2.5), and switching to selective serotonin reuptake inhibitor (5.1 ± 2.4).ConclusionPrimary care physicians exercise caution when prescribing benzodiazepine anxiolytics for unspecified anxiety disorder. Nonpharmacological interventions and switching to SSRI are modestly employed as primary treatment options and alternatives to benzodiazepine anxiolytics. To ensure the safe and effective treatment of unspecified anxiety disorder in primary care, more information should be provided from field experts.

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Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical practice for unspecified anxiety disorder in primary care

Sakurai

Takeshima

Inada³

et al. 2023

PCN Reports

Self Cite

View full text Add to dashboard Cite

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Management of unspecified anxiety disorder: Expert consensus

Sakurai

Inada

Aoki

et al. 2023

Neuropsychopharm Rep

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Aims: Treatment guidelines with respect to unspecified anxiety disorder have not been published. The aim of this study was to develop a consensus among field experts on the management of unspecified anxiety disorder. Methods:Experts were asked to evaluate treatment choices based on eight clinical questions concerning unspecified anxiety disorder using a nine-point Likert scale (1 = "disagree" to 9 = "agree"). According to the responses from 119 experts, the choices were categorized into first-, second-, and third-line recommendations.Results: Benzodiazepine anxiolytic use was not categorized as a first-line recommendation for the primary treatment of unspecified anxiety disorder, whereas multiple nonpharmacological treatment strategies, including coping strategies (7.9 ± 1.4), psychoeducation for anxiety (7.9 ± 1.4), lifestyle changes (7.8 ± 1.5), and relaxation techniques (7.4 ± 1.8), were categorized as first-line recommendations. Various treatment strategies were categorized as first-line recommendations when a benzodiazepine | 189 SAKURAI et al.

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The Efficiency of Binaural Beats on Anxiety and Depression—A Systematic Review

Baseanu,

Roman,

Minzatanu

et al. 2024

Applied Sciences

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Anxiety and depression are two of the most impactful diseases on quality of life and cause significant disability to patients. It burdens the medical system even as a stand-alone pathology or a secondary condition. These conditions can occur secondarily after a patient suffers from other illnesses, such as upper motor neuron lesions. Binaural beats are a new and emerging type of technology that can be used as an adjunct therapy for anxiety and depression as well as in neurologic conditions to some extent. We searched through the MEDLINE, PsychINFO, EMBASE, CENTRAL, ISRCTN, and ICTRP databases to identify studies using binaural beats as therapy for anxiety and depression. Twelve articles were declared eligible to be included in this review. Binaural beats, whether used in the form of pure beats or masked by another sound, have shown better results in alleviating symptoms of anxiety and depression compared to control conditions such as no music or the use of noise-canceling headphones alone. The results suggest that using binaural beats could be a promising and easy-to-use method to help alleviate the symptoms of anxiety and depression.

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Management of unspecified anxiety disorder: Expert consensus

Cited by 3 publications

References 22 publications

Clinical practice for unspecified anxiety disorder in primary care

Clinical practice for unspecified anxiety disorder in primary care

Management of unspecified anxiety disorder: Expert consensus

The Efficiency of Binaural Beats on Anxiety and Depression—A Systematic Review

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