Management of umbilical granuloma in infants: A systematic review of randomised controlled trials

Jois, Ravisha Srinivas; Rao, Shripada

doi:10.31128/ajgp-04-20-5371

Cited by 4 publications

(2 citation statements)

References 15 publications

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“…10 In 2021, a systematic review of randomised controlled trials for studying the effects of topical treatments for UG reported that common salt resolved granuloma in >90% of infants in five studies, while resolved 54%-80% in two studies with excellent safety profile and no side effects. 11 The results of the present study are also similar to the data published by others and mentioned above. The study observed a 90% cure rate in infants with age between 3-8 weeks (5.64±1.66 weeks) including both genders.…”

Section: Discussionsupporting

confidence: 93%

Efficacy of common salt application on the umbilical granuloma in infants

Faizan Sadiq,

Ahmad

2023

J Pak Med Assoc

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The objective of this study was to determine the efficacy of the application of common plain salt for the treatment of umbilical granuloma in infants. The study design was descriptive case series and was conducted over a period of 12 months at the paediatric unit, Mardan Medical Complex, Mardan, Pakistan. For this study a total of 50 infants with clinically evident umbilical granuloma were selected. Application of a pinch of common plain salt was advised on the granuloma twice a day for three consecutive days. Outcomes in the shape of complete resolution of the granuloma, adverse effects, and recurrence of granuloma were assessed. The number of patients responding well to the treatment was 45 (90%). The treatment showed good response and there was not any adverse effect or recurrence. ---Continue

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Section: Discussionsupporting

confidence: 93%

Efficacy of common salt application on the umbilical granuloma in infants

Faizan Sadiq,

Ahmad

2023

J Pak Med Assoc

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“…Umbilical Granulomas are one of the commonest anomalies of the umbilicus in the newborn 1 . They present as a small granulation tissue at the base of the umbilicus 2 , (Figure 1).…”

Section: Introductionmentioning

confidence: 99%

Up to Date Management of Umbilical Cord Granuolmas

Article

2023

AJMCRR

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Umbilical granulomas are of common occurrence in the neonatal period. The diagnosis is triggered by the observation of umbilical discharge and the identification of a red granulation tissue mass at the base of the umbilical stump. The clinicians should practice extra vigilance to differentiate the benign Umbilical Granuloma from other serious diagnoses involving the remnants of the umbilical cord including Patent Urachus and Persistent Vitello Intestinal Duct. Identification of urine or stool within the discharge material should alert the Paediatrician or Paediatric Surgeon to such diagnoses. Other differential diagnoses include Umbilical Polyp, Urachal Duct Cyst, Haemangiomas and Pyogenic Granuloma. The association of an infected Umbilical Granuloma with Omphalitis and Necrotizing Fasciitis has persuaded many Neonatologist and Paediatric Surgeons to abandon the expectant management approach. However, there is as yet, no universally agreed management strategy for Umbilical Granulomas. Active management options include topical application of Common Salt, Silver Nitrate, Copper Sulphate, Alcohol Wipes, topical Corticosteroids, topical Doxycycline Powder, Silk ligation, surgical excision, Cryocautery, and Electrocautery. The conclusion of our extensive research is that the majority of the interventions are effective in treating Umbilical Granulomas. However, Common Salt application appears to be the most practical, simple and effective option, with no reported complications.

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