“…Epinephrine is still the primary drug for anaphylaxis (10), but avoidance of medications, which contain metabisulfites as preservatives, including epinephrine, has been suggested for patients with definite allergy to sulfites. Methoxamine, a potent alpha agonist, should be an alternative for cases not responding to multiple doses of epinephrine or in cases in which epinephrine is contraindicated (11).…”