Management of internal inflammatory root resorption using injectable platelet-rich fibrin revascularization technique: a clinical study with cone-beam computed tomography evaluation

Nageh, Mohamed; Ibrahim, Lamiaa A.; AbuNaeem, Fatma M; Salam, Engy Ali Abdelhaleem

doi:10.1007/s00784-021-04123-z

Cited by 7 publications

(27 citation statements)

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…27,28 In a final clinical study, Negah and colleagues investigated i-PRF administration for the management of root resorption in 10 healthy patients. 29 It was reported that the clinical evaluation resulted in the resolution of signs and symptoms through a 12-month follow-up period in all cases. Moreover, the radiographic evaluation showed a marked decrease in the mean volume of internal inflammatory root resorption and periapical lesions.…”

Section: Us E Of I-prf For Improved Wound He Aling In the Or Al C Avit Ymentioning

confidence: 93%

“…It was reported that the clinical evaluation resulted in the resolution of signs and symptoms through a 12‐month follow‐up period in all cases. Moreover, the radiographic evaluation showed a marked decrease in the mean volume of internal inflammatory root resorption and periapical lesions 29 . Finally, an additional four studies found that i‐PRF demonstrated antimicrobial efficacy against both periodontal and cariogenic pathogens 30–33 …”

Section: Use Of I‐prf For Improved Wound Healing In the Oral Cavitymentioning

confidence: 96%

“…Moreover, the radiographic evaluation showed a marked decrease in the mean volume of internal inflammatory root resorption and periapical lesions. 29 Finally, an additional four studies found that i-PRF demonstrated antimicrobial efficacy against both periodontal and cariogenic pathogens. [30][31][32][33]…”

Section: Us E Of I-prf For Improved Wound He Aling In the Or Al C Avit Ymentioning

confidence: 99%

“…Two further studies demonstrated that i‐PRF injections significantly improved symptomatic oral lichen planus 27,28 . In a final clinical study, Negah and colleagues investigated i‐PRF administration for the management of root resorption in 10 healthy patients 29 . It was reported that the clinical evaluation resulted in the resolution of signs and symptoms through a 12‐month follow‐up period in all cases.…”

Section: Use Of I‐prf For Improved Wound Healing In the Oral Cavitymentioning

confidence: 99%

See 3 more Smart Citations

Ten years of injectable platelet‐rich fibrin

Miron,

Gruber,

Farshidfar

et al. 2023

Periodontology 2000

View full text Add to dashboard Cite

The use of platelet‐rich fibrin (PRF) has seen widespread advantages over platelet‐rich plasma (PRP) in many fields of medicine. However, until 2014, PRF remained clinically available only in its solid clotted form. Modifications to centrifugation protocols and tube technology have led to the development of a liquid injectable version of PRF (i‐PRF). This narrative review takes a look back at the technological developments made throughout the past decade and further elaborates on their future clinical applications. Topics covered include improvements in isolation techniques and protocols, ways to further concentrate i‐PRF, and the clinical impact and relevance of cooling i‐PRF. Next, various uses of i‐PRF are discussed, including its use in regenerative periodontology, implantology, endodontics, temporomandibular joint injections, and orthodontic tooth movement. Furthermore, various indications in medicine are also covered, including its use in sports injuries and osteoarthritis of various joints, treatment of diabetic ulcers/wound care, and facial esthetics and hair regrowth. Finally, future applications are discussed, mainly its use as a drug delivery vehicle for small biomolecules, such as growth factors, antibiotics, exosomes, and other medications that may benefit from the controlled and gradual release of biomolecules over time.

show abstract

Section: Us E Of I-prf For Improved Wound He Aling In the Or Al C Avit Ymentioning

confidence: 93%

Section: Use Of I‐prf For Improved Wound Healing In the Oral Cavitymentioning

confidence: 96%

Section: Us E Of I-prf For Improved Wound He Aling In the Or Al C Avit Ymentioning

confidence: 99%

Section: Use Of I‐prf For Improved Wound Healing In the Oral Cavitymentioning

confidence: 99%

See 2 more Smart Citations

Ten years of injectable platelet‐rich fibrin

Miron,

Gruber,

Farshidfar

et al. 2023

Periodontology 2000

View full text Add to dashboard Cite

show abstract

“…According to some studies, pulp revascularization of immature teeth with infected necrotic pulps and/or teeth with apical periodontitis was possible and even predictable (Deluca et al, 2021). The procedure requires disinfection of the pulp space with an effective antibacterial regimen, production of a clot in the pulp space, cervical sealing, and a definitive restoration (Nageh, 2022;Ravikumar, 2021). Thus, regenerative endodontic procedures may improve the prognosis of the immature tooth Research, Society and Development, v. 12, n. 1, e15012139771, 2023 (CC BY 4.0) | ISSN 2525-3409 | DOI: http://dx.doi.org/10.33448/rsd-v12i1.39771 3 compromised by the restoration of functional pulp tissue (Bakhtiar et al, 2022;Caleza-Jiménez, 2022;He, 2022;Law, 2013;Lenzi, 2012).…”

Section: Introductionmentioning

confidence: 99%

Regenerative therapy in young permanent tooth: Case report

Araújo

Casadei²,

Chaves³

2023

RSD

View full text Add to dashboard Cite

Pulp necrosis in immature permanent teeth represents a challenge for clinical management. The dentin wall in immature teeth is thin and the root is short, leading to an unfavorable long-term prognosis due to the risk of root fracture. Regenerative endodontic procedures have been shown to be effective and improve the prognosis of the compromised immature tooth by re-establishing functional pulp tissue that promotes continued root development and immune competence. The objective of the study was to report a case of a young permanent molar, diagnosed with necrosis and incomplete rhizogenesis. A female patient, 08 years old, attended the clinic of the specialization course in Endodontics, Faculty of Dentistry São Leopoldo Mandic, Belo Horizonte Unit. Regenerative therapy was proposed, which involved the following steps: anesthesia, opening, odontometry, minimal instrumentation, disinfection with 2% chlorhexidine gel, irrigation with saline solution, intracanal medication with calcium hydroxide paste, induction of bleeding to form a blood clot, cervical sealing with mineral trioxide aggregate and composite resin. The patient remained symptom-free up to 5 months after treatment. However, radiographically, an increase in the periapical radiolucent area was noted, so it was decided to carry out the conventional endodontic treatment. Regenerative therapy can be an alternative to apexification in immature teeth in cases of irreversible pulpitis and pulp necrosis associated or not with a periapicalesionson. It is a simple treatment with advantageous results as it promotes an increase in the length and thickness of the dentin wall and apical closure as seen in the case described in this work.

show abstract