Management of Hyperglycemic Crises

Fayfman, Maya; Pasquel, Francisco J.; Umpiérrez, Guillermo E.

doi:10.1016/j.mcna.2016.12.011

Cited by 170 publications

(135 citation statements)

References 121 publications

(176 reference statements)

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“…Diabetic ketoacidosis (DKA) is a life-threatening and serious complication of diabetes (American Diabetes A, 2014). DKA is more common in young people suffering from T1DM and is characterized by a lack of insulin, severely high levels of blood glucose, metabolic acidosis and ketosis (Fayfman et al, 2017;Modi et al, 2017). Continuous insulin injection and repeated low-dose injections of insulin are common treatments for DKA and are simple, safe and effective (Dhatariya and Vellanki, 2017).…”

Section: Diabetic Ketoacidosismentioning

confidence: 99%

“…HHS has a lower hospitalization rate and higher mortality rate than DKA (Fayfman et al, 2017). Current treatment options are fluid and electrolyte infusion or insulin infusion; certain minerals, such as sodium and potassium, can be quickly replaced during treatment; however, the treatment process is complicated and may cause electrolyte imbalance (Bhowmick et al, 2005;Fayfman et al, 2017;Baldrighi et al, 2018). Therefore, early diagnosis and management are vital in HHS treatment.…”

Section: Hyperosmolar Hyperglycemic Statusmentioning

confidence: 99%

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Adjuvant Therapy With Mushroom Polysaccharides for Diabetic Complications

Jiang

Meng

et al. 2020

Front. Pharmacol.

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Background: Diabetic complications seriously endanger the health of most diabetic patients around the world. Most chemical hypoglycemic agents have adverse effects and are unable to improve the progression of diabetic complications. In recent years, a number of medicinal herbs have become increasingly popular for the treatment of diabetic complications due to their relative safety. Polysaccharides extracted from medicinal herbs with multiple pharmacological activities and low toxicity have been reported to be useful in the treatment of diabetic complications. Methods: Primary studies with keywords including polysaccharide and diabetic complications were retrieved from the Web of Science and NCBI databases and were read and analyzed. Results: Mushroom polysaccharides were proven to have positive effects on diabetic complications. Conclusions: We studied the effects of mushroom polysaccharides on hyperglycemia and as adjuvant therapies for diabetic complications and summarized the applications and limitations of mushroom polysaccharides to better understand their application for the treatment of diabetic complications.

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Section: Diabetic Ketoacidosismentioning

confidence: 99%

Section: Hyperosmolar Hyperglycemic Statusmentioning

confidence: 99%

Adjuvant Therapy With Mushroom Polysaccharides for Diabetic Complications

Jiang

Meng

et al. 2020

Front. Pharmacol.

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“…The differential diagnosis of hyperglycaemic-hyperosmolar state should include acute disorders of the central nervous system, coma resulting from poisoning or coma of other origins, including hypoglycaemic, liver, brain, uremic or ketone disorders [21,22].…”

Section: Hyperglycaemic-hyperosmolar State -Hhsmentioning

confidence: 99%

Emergency medicine point of view on epidemiology of diabetes and diabetes-related complications

Szalast

Szarpak

2020

Disaster Emerg Med J

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INTRODUCTION: Despite centuries of research and clinical work, the diagnosis of diabetes was still treated as a quick death sentence at the beginning of the 20th century. Unfortunately, the number of patients with diabetes is increasing every year. Type 2 diabetes is increasingly common among young people: children and adolescents. The article discusses the type of diabetes and the importance of rapid diagnosis and management. Type 1 diabetes, type 2 diabetes, latent autoimmune diabetes in adults, monogenic diabetes, gestational diabetes were analysed. Life-threatening conditions resulting from complications of diabetes including diabetic ketoacidosis, hyperglycaemic-hyperosmolar state, hypoglycaemia, lactic acidosis were discussed, and the first-line emergency treatment were analysed. The life-threatening complications of diabetes and rescue procedures in these conditions were discussed in detail. CONCLUSIONS: Due to the frequency of life-threatening complications, diabetes is a heavy burden on the medical staff. Adequate diagnosis and implementation of appropriate treatment significantly improve the patient's condition.

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“…The described syndrome is an acute metabolic disorder characterized by hyperglycemia, ketones bodies and metabolic acidosis. Its prognosis is not that good and still remains a disorder with high mortality rate [4].…”

Section: Introductionmentioning

confidence: 99%

“…All these findings were present in our patient's investigations. The treatment of diabetic ketoacidosis has mainly the goal to hydrate the patient and decrease the level of glucose in the blood, in order to control the acid-base balance [4].…”

Section: Introductionmentioning

confidence: 99%

Case Report: Emphysematous Pyelonephritis Triggers Diabetic Ketoacidosis in a 60 Years Old Patient

Kapellos¹

2018

J Diabetes Metab

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The report describes the case of a 60 years old female patient admitted in our emergency department with main complaints of abdominal pain, malaise, fever and oliguria the last three days. The primary blood samples investigations revealed leukocytosis, acute renal function impairment and increased serum glucose. The patient is known with diabetes type II for the last fifteen years, has been in treatment with metformin and basic insulin therapy but the disease remains not well controlled. Further laboratory investigation and physical examination were consistent with the diagnosis of diabetic ketoacidosis. The urine examination showed pyuria leading to the diagnosis of a urinary tract infection. The abdominal XRAY was without abnormal findings but in the ultrasound and abdominal CT, a few renal parenchymatic lesions have been observed, more clearly seen on the CT. The presence of air within the tissue was consistent with a very rare and life-threatening infection, known as emphysematous pyelonephritis. The patient was put on the necessary treatment.

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Management of Hyperglycemic Crises

Cited by 170 publications

References 121 publications

Adjuvant Therapy With Mushroom Polysaccharides for Diabetic Complications

Adjuvant Therapy With Mushroom Polysaccharides for Diabetic Complications

Emergency medicine point of view on epidemiology of diabetes and diabetes-related complications

Case Report: Emphysematous Pyelonephritis Triggers Diabetic Ketoacidosis in a 60 Years Old Patient

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