Management of Herpetic Urethritis and Female Partners of Men With Nongonococcal Urethritis

Handsfield, H. Hunter

doi:10.1097/olq.0000000000000579

Cited by 1 publication

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References 12 publications

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“…Mycoplasma and chlamydia are common sexually transmitted pathogens in males and females, both of which can cause stubborn infections that cannot be cured by antibiotics. The resulting disease from a resistant pathogen is difficult to cure and prone to recurrence (20,21). Since the primary route of transmission of NGU is sexual, the incidence of NGU has increased rapidly in recent years, and it has become primarily a sexually transmitted disease.…”

Section: Discussionmentioning

confidence: 99%

Azithromycin combined with doxycycline in non‑gonococcal urethritis

Hou

et al. 2020

Exp Ther Med

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Non-gonococcal urethritis (NGU) is one of the most common sexually transmitted diseases caused by chlamydia or mycoplasma. The present study aimed to explore the clinical efficacy of azithromycin combined with doxycycline in patients with NGU and its effect on serum levels of inflammatory cytokine interleukin-6 (IL-6).A total of 98 patients with non-gonococcal urethritis were prospectively selected, of which 46 patients were assigned to an azithromycin group (treated with azithromycin alone), while the rest were assigned to a combination group (treated with azithromycin and doxycycline). The conditions of the patients were evaluated and compared between the two groups. The treatment efficacy in patients in the combination group was significantly better than that in the azithromycin group, and the time to symptom relief, period of medication, recurrence rate within 1 year of withdrawal and level of serum IL-6 in the combination group were significantly lower than those in the azithromycin group. The quality of life of patients in the combination group was significantly improved compared to those in the azithromycin group. However, there was no significant difference in the incidence of adverse reactions between the two groups. Azithromycin combined with doxycycline was revealed to be more effective than azithromycin monotherapy for NGU.

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Section: Discussionmentioning

confidence: 99%

Azithromycin combined with doxycycline in non‑gonococcal urethritis

Hou

et al. 2020

Exp Ther Med

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Management of Herpetic Urethritis and Female Partners of Men With Nongonococcal Urethritis

Cited by 1 publication

References 12 publications

Azithromycin combined with doxycycline in non‑gonococcal urethritis

Azithromycin combined with doxycycline in non‑gonococcal urethritis

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