Management of complicated meconium ileus

Neonatal spontaneous colonic perforation due to cystic fibrosis

“…Colonic perforation is less well recognised. There are sporadic reports of colonic perforation in reviews of meconium ileus in the literature (Table 1) [4][5][6][7][8][9].…”

Surgical management of pulmonary and gastrointestinal complications in children with cystic fibrosis

“…The treatment of complicated meconium ileus almost always requires an operation [67], an exception being the rare in-utero perforation that has left a telltale remnant of extraluminal intraperitoneal calcified meconium, but the perforation spontaneously has sealed. Meconium peritonitis may be seen as one of several varieties.…”

Meconium Ileus

“…14 There are four typical presentations of complicated meconium ileus including meconium pseudocyst with a calcified fibrous wall and bowel loops peripheral and usually posterior to the cyst, dense vascular adhesions with scattered calcifications, meconium ascites, and infected meconium ascites. 26,29 Again, creation of an ostomy is usually necessary to relieve the obstruction and for ongoing irrigation postoperatively. In some of these cases such as meconium cyst, the bowel may be very difficult to find and may be hidden posterior to the cyst rind.…”

“…23,26,51 Ostomy may be necessary for rectal strictures though pullthrough operations have been described. 29 There are small case reports of using steroids that have allowed strictures to resolve. 51…”