Mammographic and Ultrasonographic Findings of Different Breast Adenosis Lesions

Abstract

Aim: To describe imaging features of different breast adenosis lesions.Materials and methods: Mammographic and ultrasonographic findings of patients with different types of adenosis were reviewed retrospectively Tissue samples were obtained either with US-guided core needle biopsy or localization with needle-wire system and surgical excision.Results: Forty-three adenosis lesions were diagnosed in 41 patients: 27 sclerosing adenosis, 13 blunt duct adenosis and 3 microglandular adenosis. Most frequent abnormal findings of sclerosing adenosis were masses with non-circumscribed margins and focal acoustic shadowing without mass configuration (54%) on ultrasonography. Mammography was normal in 54% of sclerosing adenosis, the most common abnormality was architectural distortion (21%). In blunt duct adenosis, usually circumscribed masses (46%) were detected on ultrasonography, clustered punctate microcalcifications (23%) and circumscribed masses (23%) were observed on mammography. All microglandular adenosis lesions were non-circumscribed masses. Premalignant components were detected only with surgical excisional biopsy in three patients that showed suspicious radiological findings and benign pathological result on core biopsy.Conclusion: The adenosis lesions have no pathognomonic characteristics on mammography and ultrasound. Total excision may be considered when suspicious radiological findings are present although core needle biopsy results are benign.

Efficacy and safety of percutaneous ultrasound—guided vacuum—assisted excision for the treatment of clinical benign breast lesions larger than 3 cm: a retrospective cohort study

“…Breast adenosis, which is normally not considered a premalignant lesion, is histological hyperplasia that involves the glandular component of the breast. However, it has been considered to be associated with breast cancer, especially for sclerosing and microglandular adenosis ( 19 ). Thus, the excision of adenosis is essential for those patients.…”

Ultrasound‐Based Nomogram for Distinguishing Malignant Tumors from Nodular Sclerosing Adenoses in Solid Breast Lesions

“…Our nomogram is different from the traditional BI‐RADS categorization scheme. Previous studies could not differentiate NSA and MT through ultrasonic features and BI‐RADS category 28,29 . One study has shown that the US BI‐RADS atlas together with breast elastography may be a powerful tool to identify NSA and differentiate it from breast cancer 25 .…”

Chest

“…They are commonly seen along the inframammary fold, cleavage area, overlying the axilla, and around the areola. If superficial in location, a tangential view is needed to confirm that they are dermal versus parenchymal [169]. Tattoo sign is important because it may be the only clue that suggests the dermal location of microcalcifications when other characteristics of dermal calcification are not present.…”

“…Calcifications do not change orientation between the craniocaudal and the mediolateral oblique projections or from year to year. The tattoo sign is characteristic of benign skin calcifications [169] important to differentiate the microcalcifications of benign origin from those that are suspicious, because 55% of nonpalpable cancers are diagnosed by the presence of microcalcifications, and because microcalcifications are the main form of manifestation of ductal carcinoma in situ (DCIS). Some of these calcifications correspond not only to pure DCIS but also to the intraductal portion of infiltrating carcinomas.…”