Mammary Silicone Granuloma

Medical‐Grade Fluid Silicone: A Monographic Review

“…Putatively safe and effective materials touted for augmentation of soft tissue came to be administered in massive doses by unqualified individuals and outright charlatans who injected “secret formulas.” The consequences were disastrous ,,,. Fiascos became well publicized and were misrepresented as resulting from use of “silicone.” The fact is that some of the injected concoctions contained no polydimethylsiloxane at all …”

Ten‐Year Experience Using Injectable Silicone Oil for Soft Tissue Augmentation in the Philippines

“… Not all adverse reactions are caused by impure silicone or poor technique 1,2. Although severe complications of pure liquid silicone are rare, they do occur, often in association with allergies and infectious processes, and may be triggered by certain classes of drugs. Not all complications are easily treated 3 Liquid silicone is extremely technique sensitive and unforgiving.…”

“…Many reports of adverse reactions,2–10 such as granulomas6–8 (one delayed up to 7 years), surface deformities, infections, necrosis, rosacea‐like reactions, migration (high volumes), lymph vessel blockage, embolism, blindness, asymmetry, distortion, allergies, lipoatrophy, recurrent edema with or without erythema or idiosyncrasy, and sensorial changes with large volumes,10 showed that these were caused by adulterated silicone, used in areas not indicated, using incorrect techniques and injecting large volumes.…”

Comparison of Injectable Silicone Versus Collagen for Soft Tissue Augmentation

“…The literature is filled with horrible case reports of serious complications. A brief list would include bilateral breast necrosis, progressive fibrous and peau d'orange lymphedema, pneumonitis from embolization, and chronic inflammation with granuloma formation of breasts, face, extremities, and penis 1,2,8,9,10,11 . However, in all of these cases, the material was either not medical grade silicone or was improperly used.…”