Malnutrition-Related Diabetes Mellitus (MRDM), Not Diabetes-Related Malnutrition: A report on genuine MRDM

Chattopadhyay, Partha Sarathi; Gupta, Sanjib Kumar; Chattopadhyay, Rita; Kundu, Prabir Kumar; Chakraborti, R. N.

doi:10.2337/diacare.18.2.276

Cited by 7 publications

(3 citation statements)

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“…Some investigators hypothesized that consumption of cassava (manioc or tapioca) could lead to diabetes in malnourished subjects, due to cyanogenic glycosides leading to chronic pancreatitis; however, the theories remained largely speculative ( 232 ). Others postulated that chronic protein energy malnutrition would cause persistent insulin deficiency and glucose intolerance without ketosis, among other clinical features ( 234 – 236 ).…”

Section: Etiology Of Type 2 Dm In Hispanics/latinosmentioning

confidence: 99%

From Sea to Shining Sea and the Great Plains to Patagonia: A Review on Current Knowledge of Diabetes Mellitus in Hispanics/Latinos in the US and Latin America

et al. 2017

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The past two decades have witnessed many advances in the prevention, treatment, and control of diabetes mellitus (DM) and its complications. Increased screening has led to a greater recognition of type 2 diabetes mellitus (type 2 DM) and prediabetes; however, Hispanics/Latinos, the largest minority group in the US, have not fully benefited from these advances. The Hispanic/Latino population is highly diverse in ancestries, birth places, cultures, languages, and socioeconomic backgrounds, and it populates most of the Western Hemisphere. In the US, the prevalence of DM varies among Hispanic/Latino heritage groups, being higher among Mexicans, Puerto Ricans, and Dominicans, and lower among South Americans. The risk and prevalence of diabetes among Hispanics/Latinos are significantly higher than in non-Hispanic Whites, and nearly 40% of Hispanics/Latinos with diabetes have not been formally diagnosed. Despite these striking facts, the representation of Hispanics/Latinos in pharmacological and non-pharmacological clinical trials has been suboptimal, while the prevalence of diabetes in these populations continues to rise. This review will focus on the epidemiology, etiology and prevention of type 2 DM in populations of Latin American origin. We will set the stage by defining the terms Hispanic, Latino, and Latin American, explaining the challenges identifying Hispanics/Latinos in the scientific literature and databases, describing the epidemiology of diabetes—including type 2 DM and gestational diabetes mellitus (GDM)—and cardiovascular risk factors in Hispanics/Latinos in the US and Latin America, and discussing trends, and commonalities and differences across studies and populations, including methodology to ascertain diabetes. We will discuss studies on mechanisms of disease, and research on prevention of type 2 DM in Hispanics/Latinos, including women with GDM, youth and adults; and finalize with a discussion on lessons learned and opportunities to enhance research, and, consequently, clinical care oriented toward preventing type 2 DM in Hispanics/Latinos in the US and Latin America.

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Section: Etiology Of Type 2 Dm In Hispanics/latinosmentioning

confidence: 99%

From Sea to Shining Sea and the Great Plains to Patagonia: A Review on Current Knowledge of Diabetes Mellitus in Hispanics/Latinos in the US and Latin America

et al. 2017

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“…Severely malnourished people have been shown to have hypoglycaemia and diabetes, but this was observed mostly in developing countries . Recently, elevated malnutrition risk measured at hospital admission using the Nutrition Risk Screen 2002 was found to predict hypoglycaemia among hospitalized individuals regardless of diabetes status .…”

Section: Introductionmentioning

confidence: 99%

Association of albumin and cholesterol levels with incidence of hypoglycaemia in people admitted to general internal medicine units

Leibovitz¹,

Wainstein

Boaz

2018

Diabet. Med.

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“…Diabetes mellitus (DM) -a major non-communicable disease -has been linked to both chronic under nutrition [4,5] and obesity [3], although its relationship with chronic under nutrition has remained a subject of debate [6]. Previously, DM in children was essentially insulin-dependent (IDDM) or type 1 DM, but non-insulin dependent (NIDDM) or type 2 DM is now becoming more common in young adults, teens and children; obesity is the major type 2 diabetes risk.…”

Section: Introductionmentioning

confidence: 99%

Childhood Diabetes Mellitus and the Double Burden of Malnutrition: An Emerging Public Health Challenge in Developing Countries

Uwaezuoke¹

2015

J Diabetes Metab

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The 'double burden of malnutrition' refers to the simultaneous existence of both undernutrition and overnutrition in the same population across the life course. Diabetes mellitus (DM) -a major non-communicable disease -has been linked to both chronic undernutrition and obesity; the latter is now assuming prominence in developing countries. The present review aims to highlight the global burden of this non-communicable disease in children and its relationship with the 'double burden of malnutrition'. Type 2 DM has rapidly evolved from a disease of the Western world to a global disease; from a disease of affluence to a disease that now afflicts the poor; and from an adult-onset disease to a disease that is gaining prominence in the pediatric population. Estimates from the International Diabetes Federation show that diabetes affects at least 285 million people worldwide out of which two-thirds occur in developing (low-to middle-income) countries. The global epicenter of diabetes epidemic is located in China and India as Asia has undergone rapid economic development, urbanization and transitions in nutritional status. Overweight and obesity are propelling the worldwide diabetes epidemic. Central obesity is correlated with both insulin resistance and type 2 DM. Moreover, the scourge of chronic undernutrition among children in tropical developing countries may predispose them to malnutrition-modulated diabetes mellitus (MMDM) later in life. Children in these regions are thus faced with a health-related dilemma. There is an urgent need to develop a comprehensive prevention program targeted at reducing diabetes risk and promoting proper nutrition among children in these countries.

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Malnutrition-Related Diabetes Mellitus (MRDM), Not Diabetes-Related Malnutrition: A report on genuine MRDM

Cited by 7 publications

References 0 publications

From Sea to Shining Sea and the Great Plains to Patagonia: A Review on Current Knowledge of Diabetes Mellitus in Hispanics/Latinos in the US and Latin America

From Sea to Shining Sea and the Great Plains to Patagonia: A Review on Current Knowledge of Diabetes Mellitus in Hispanics/Latinos in the US and Latin America

Association of albumin and cholesterol levels with incidence of hypoglycaemia in people admitted to general internal medicine units

Childhood Diabetes Mellitus and the Double Burden of Malnutrition: An Emerging Public Health Challenge in Developing Countries

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