Maligne Tumoren des Rektums

Gall, F. P.; Scheele, J.

doi:10.1007/978-3-642-69600-8_29

Cited by 9 publications

(7 citation statements)

References 135 publications

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“…Lymph node métastasés were found in pTi cancer in 9-25% of the cases [18,19]. On the other hand low risk pT| cancer has a risk of only 3% and low risk pT2 cancer of 12% of lymph node metastasis [4,15], whereas high risk cancer has a risk of 56-72% of lymph node metastasis [1,20].…”

Section: Discussionmentioning

confidence: 99%

Influence of Histomorphological Parameters and Ploidy on Recurrence-Free Survival Time in Early Rectal Cancer after Local Excision

Böttger¹,

Heinz²,

Potratz³

et al. 1993

Dig Surg

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The aim of this study was to evaluate the prognostic influence of histomorphological parameters and ploidy on recurrence-free survival time in early rectal cancer, after local excision in 47 patients. In this prospective study with a mean follow-up of 35 months (range 0-79 months) a strong correlation was found between the ploidy and the histomorphological parameters. In a multivariate analysis the radicality of the excision and the ‘low and high risk’ classification were of prognostic significance. The DNA content of tumor cells only had a weak influence on prognosis. Both surgeon and pathologist therefore play an important role in the long-term results after local excision of early rectal cancer.

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Section: Discussionmentioning

confidence: 99%

Influence of Histomorphological Parameters and Ploidy on Recurrence-Free Survival Time in Early Rectal Cancer after Local Excision

Böttger¹,

Heinz²,

Potratz³

et al. 1993

Dig Surg

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“…[9][10][11][12][13][14][15][16][17][18] Ten main groups of lymph nodes can be differentiated, some of which can be subdivided. The lateral superior parts of the gland drain to the lymph nodes of the internal jugular vein, whereas the lymph vessels of the medial superior regions run to the prelaryngeal nodes.…”

Section: Regional Lymph Nodes Lnn Parotidei Superficiales Et Profundmentioning

confidence: 99%

“…[13][14][15][16][17][18], can be found below the insertion of the sternocleidomastoid muscle and accompanying the accessory nerve posteriorly beneath the trapezius muscle. cervicales profundi: these nodes receive lymph from almost all head and neck nodes.…”

Section: Lnn Cervicales Lateralesmentioning

confidence: 99%

“…spaces, where they penetrate the intercostal muscles and terminate in the internal mammary lymph nodes (Lnn. 5,6,(11)(12)(13)(14)(15)(16)(17)(18): behind the pharynx in front of the prevertebral fascia and muscles (Lnn. These lymph nodes are very small in diameter (2-5 mm) and can be found in close relationship to the internal mammary vessels within 3 cm of the sternal edge.…”

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confidence: 99%

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Normal Lymph Node Topography

Richter¹,

Feyerabend²

2004

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“…This decision-making system is based not only on the abovediscussed histopathological and clinical features, but also on the experience and end results obtained in the Department of Surgery of the University of Erlangen [6,7,9,10,12,24,25,26,28,39]. Figure 5 illustrates the development of the overall and recur rence-free survival rates achieved in Erlangen from 1969 to 1987.…”

Section: Decision-making Systemmentioning

confidence: 99%

Decision-making in Curative Rectum Carcinoma Surgery

Hohenberger¹,

Hermanek²,

Gall³

1992

Oncol Res Treat

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Rectal carcinomas are increasingly treated by more and more differentiated regimens. Until the 1970s, the rectal excision was standard, whereas in 58% sphincter-saving procedures were performed during the last years. Locoregional recurrences are the main problem of surgical treatment for rectum carcinomas. They are of decisive importance for the patients. Without locoregional recurrence during the first two years, the overall five-year survival is 85% which decreases tremendously to 23% in case of a locoregional recurrence. Overall, this rate depends primarily on patho-histological parameters of the primary, as well as on therapeutic modalities and quality, too. For this reason, the arguments for routine neo- or adjuvant radio-(chemo-)therapy, increasingly arising during the last two years, is debatable. Global recommendations do not realize that low rates of locoregional recurrences may be achieved by surgery alone, e.g., 13% in the surgical Department of the University of Erlangen. However, these patients do include some groups with increased risk, for example, those who have positive lymph nodes along the course of a named vascular trunk (18%). These patients at increased risk may profit from adjuvant-radio-(chemo-)therapy. This is not yet, however, proven by any prospective study.

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Maligne Tumoren des Rektums

Cited by 9 publications

References 135 publications

Influence of Histomorphological Parameters and Ploidy on Recurrence-Free Survival Time in Early Rectal Cancer after Local Excision

Influence of Histomorphological Parameters and Ploidy on Recurrence-Free Survival Time in Early Rectal Cancer after Local Excision

Normal Lymph Node Topography

Decision-making in Curative Rectum Carcinoma Surgery

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