Malignant thoracopulmonary small-cell ("Askin") tumor

Fink, Ira J.; Kurtz, D.; Cazenave, Lorranie A.; Lieber, Michael R.; Miser, James S.; Chandra, Rakesh; Triche, T J

doi:10.2214/ajr.145.3.517

Cited by 33 publications

(11 citation statements)

References 8 publications

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“…(5) Ipsilateral hilar and mediastinal adenopathy and pneumothorax are other rare findings. (6) MR imaging show heterogeneous lesions with signal intensity isointense to spinal cord on T1 weighted images and hyperintense on T2 weighted and proton density images. Direct invasion into surrounding structures can be beautifully demonstrated on MR imaging.…”

Section: Pathological Discussionmentioning

confidence: 99%

Peripheral Primitive Neuroectodermal Tumour of the Pleura in a Young Adult- A Case Report

Thamba¹,

Malhotra²

2017

jemds

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Section: Pathological Discussionmentioning

confidence: 99%

Peripheral Primitive Neuroectodermal Tumour of the Pleura in a Young Adult- A Case Report

Thamba¹,

Malhotra²

2017

jemds

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“…Its histogenesis is uncertain and would result from the migration of cells from the neural crest during the embryonic life [2]. This type of tumor is diagnosed most of the time during the second decade by the life and prevails in the female genital organ (75%) [1] [3].…”

Section: Discussionmentioning

confidence: 99%

“…On the anatomic-pathological plan, the Askin tumor appears, in a macroscopic manner, in the form of an often round or egg-shaped grey-whitish mass with multiple nodules with the presence of zones of necrosis and bleeding. Histologicaly it is turned out that a sarcoma undifferentiated proliferation in small round cells [3] [9] which raises the problem of differential diagnosis with the other PNET (Sarcoma of Ewing, Neuro epithelioma, Neuroblastoma). The recourse to immuno histochimical technic is necessary [10] [11].…”

Section: Discussionmentioning

confidence: 99%

The Rare Thoracic Tumor, Askin Tumors 7 Cases Report

Moujahid¹,

Ziadi²,

Rhari³

et al. 2014

OJTS

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The Askin tumour is a highly malignant rare tumour with small cells, pertaining to the group of the primitive neuroectodermal tumours. It develops with the costs of the soft parts of the thoracic wall and it's characterized by extra and endothoracic fast extension. We report seven cases colliged in our service by specifying the role of the imagery in the diagnosis but especially the assessment of extension of these tumours.

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“…Immunohistochemistry and electron microscopic features can distinguish it from other small cell tumours of the childhood and young adulthood. However, histologic overlap between these neoplasms usually makes differentiation difficult, especially when light microscopy alone is used [6]. These tumours can occur at any age but are more frequent in children and young adults.…”

Section: Discussionmentioning

confidence: 99%

“…Distant metastases are identified in 20-25% of newly diagnosed patients and are the most important adverse prognostic factors especially with bone or bone marrow metastasis [3]. Metastasis along the sympathetic chain has also been reported and this propensity to metastasize to nervous system may be related to its neuroectodermal origin [6]. Lymphadenopathy is uncommon [3].…”

Section: Discussionmentioning

confidence: 99%

Askin Tumour: A rare childhood thoraco -pulmonary malignancy of Ewing’s family of tumours

Mathur¹,

Jain²,

Singh³

et al. 2012

CMJ

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AbstactPrimitive neuro-ectodermal tumour of chest wall or the Askin tumour is a rare, malignant small cell neuroepithelioma that arises from the chest wall or lung. It is seen predominantly in children and adolescents. Although its appearance by light microscopy is similar to Ewing's sarcoma, rhabdomyosarcoma, neuroblastoma and lymphoma, which account for bulk of chest wall neoplasms in this age group, yet the Askin tumour is a distinct entity. We present a case of Askin tumour in a child, a rare malignant tumour in the thoraco-pulmonary area with highly aggressive clinical course.Keywords: Askin Tumour, primitive neuro-ectodermal tumour, malignant small cell neuroepithelioma ÖzetGöğüs duvarının primitif nöro-ektodermal tümörü veya diğer bir deyişle Askin tümörü nadir görülen bir küçük hücreli nöroepitelyoma olup göğüs duvarı veya akciğer kökenlidir. Ağırlıklı olarak çocuk ve adolesanlarda saptanır. Her ne kadar ışık mikroskopisindeki görünümü Ewing sarkomu, rabdomyosarkom, nöroblastom ve lenfoma gibi bu yaş grubunda çoğunlukla görülen göğüs duvarı neoplasmlarına benzese de Askin tümörü farklı bir antitedir. Bu makalede yüksek derecede agresif klinik seyirli, torakopulmoner alan yerleşimli nadir bir malignite olan Askin tümörlü bir çocuk hasta sunulmuştur.Anahtar sözcükler: Askin tümörü, primitif nöroektodermal tümör, malign küçük hücreli nöroepitelyoma Geliş tarihi

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Malignant thoracopulmonary small-cell ("Askin") tumor

Cited by 33 publications

References 8 publications

Peripheral Primitive Neuroectodermal Tumour of the Pleura in a Young Adult- A Case Report

Peripheral Primitive Neuroectodermal Tumour of the Pleura in a Young Adult- A Case Report

The Rare Thoracic Tumor, Askin Tumors 7 Cases Report

Askin Tumour: A rare childhood thoraco -pulmonary malignancy of Ewing’s family of tumours

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