Malignant recurrence and distal metastasis after complete local resection of colorectal “high-grade intraepithelial neoplasia”: incidence and risk factors

Abstract

The diagnosis of colorectal high-grade intraepithelial neoplasia based on local resection is relatively reliable. However, regarding invasion of submucosa as an indispensable criterion for malignancy may contribute to the choice of overly conservative treatment, especially in the situation that the radical resection requires removing the anus.

Features of Late Recurrence Following Transanal Local Excision for Early Rectal Cancer

“…6,9 several reports have confirmed that, as a clinically applicable modality, tae of ptis and select pt1 rectal cancers has shown oncologic outcomes similar to radical surgery. 5,10 however, local and systemic recurrences of ptis and pt1 rectal cancers following tae have been reported. 9,11 Recurrence usually occurs within 5 years after tae, but later recurrences have also been reported.…”