Malignant Perianal Papillary Hidradenoma

Hidradenoma Papilliferum of the Vulva: Report of a Case Characterized by Unusual Clinical Behavior

“…Generally, the tumor presents as a solitary lesion, 1–10 although some cases of multiple hidradenoma papilliferum have been described. Meeker et al 3 observed two patients with two hidradenomas each; Woodworth et al 4 reported a case with three hidradenomas and two cases with two, respectively.…”

“…Hidradenoma papilliferum is characterized by a round or oval‐shaped nodular lesion, often having the color of normal skin, rarely eroded 3 or ulcerated, 1,3,4 and generally smaller than 1.5 cm. Reports of lesions larger than 2 cm in size are very rare; 4,9 only Ioannides 2 observed a 4‐cm sized hidradenoma papilliferum situated on the back of a 63‐year‐old female patient.…”

“…The most common site is the vulva and in particular the labium majus. 1–5,7 Less frequently, the hidradenoma papilliferum involves the labium minus, 1–4,6 the interlabial sulcus, 1,3 the clitoris, 2 the posterior fourchette, 1,2 the mons pubis, 3 the perineum, 1,2 and the perianal and anal region 3,9 . Other sites such as the forehead, 2 the eyelid, 8 the cheek, 2 the axilla, 2 the breast nipple, 10 and the back 2 are exceptionally rare.…”

Hidradenoma Papilliferum With a Ductal Carcinoma In Situ Component: Case Report and Review of the Literature

“…1,2 The neoplasm has distinctive histopathological features previously described in detail. 3,4 Malignant variants of HP are extremely rare and have been reported as adenocarcinoma or adenosquamous carcinoma, 5,6 but the diagnosis and the histological interpretation of some of these cases have been questioned. 7 Requena et al 8 coined the term ''hidradenocarcinoma papilliferum'' for the malignant counterpart of HP and outlined the microscopic criteria for such a diagnosis.…”

Giant ectopic hidradenoma papilliferum on the scalp

“…14 Exceptional cases of malignant changes have been reported in anogenital HP, but not in any of the ectopic HP. 10,[15][16][17] As for ectopic HP, therefore, simple excision may be curative.…”