Hidradenoma Papilliferum of the Vulva: Report of a Case Characterized by Unusual Clinical Behavior

Abstract

The authors describe a case of hidradenoma papilliferum localized to the right labium majus of a 33-year-old woman. The young age of the patient, the rapid growth of the tumor, and its large size are elements that make the case atypical on the basis of the published literature.

A giant ectopic hidradenoma papilliferum in a Niger delta region of Nigeria

“…4–7,10 This may be attributed to the presence of relatively increased amount of apocrine glands in the Caucasians. 6–8 In addition, the tumour has its origin from the apocrine glands richly found in the anogenital region, vulval, perineal, axillae, and periumbilical areas.…”

“…6–8 In addition, the tumour has its origin from the apocrine glands richly found in the anogenital region, vulval, perineal, axillae, and periumbilical areas. 4–8 …”

“…9 A literature review showed that both typical and ectopic lesions are seen after puberty which agree with our study. 4,5,8–10,11,15,16 It is believed that increase in hormonal stimulation at this age group tends to foster the number of apocrine glands in the body.…”

“…1,3,10 The treatment of choice in our study was local excision which conforms to the most literature. 1,4–15 Although a few studies have reported recurrence following incomplete excision of the primary tumour. 10 Recurrence of this lesion could not be ascertained in our study, as more time is needed for this.…”

“…1 Hidradenoma papilliferum tends to originate in the apocrine glands, which are mainly concentrated in the anogenital region, vulval, perineal, axillae, and periumbilical areas. 4–8 However, the ectopic localization of this tumour is rarely reported with the most common site being the head and neck region. 8,9 …”