Malignant Odontogenic Tumors: An Update on Selected Tumors

Richardson, Mary S.; Müller, Susan

doi:10.1007/s12105-014-0584-y

Cited by 34 publications

(38 citation statements)

References 44 publications

(73 reference statements)

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“…A literature review showed that the most common age of clinical presentation of CCOC were 53-56 yr. (17-89 yr.), with female predilection (1.8:1), and the mandible (62.5%) being more commonly involved than the maxilla, with preponderance for the posterior segment [1][2][3][4][5][6][7][8][9][10][11]. Some early reviews found preponderance for the anterior segment of the jaws [10].…”

Section: Discussionmentioning

confidence: 99%

“…Some early reviews found preponderance for the anterior segment of the jaws [10]. The most commonly reported clinical symptoms were pain, localized jaw enlargement, and mobility of the involved teeth [5][6][7].…”

Section: Discussionmentioning

confidence: 99%

“…The review of literature did not help resolve our nosological dilemma on reporting our case as CCA or as CCOC. In the past the terms CCA and CCOT has been used as synonyms for CCOC [10]. Werle et al in their systematic review of 59 published cases found that 17 (29%) cases that were primarily diagnosed as ameloblastoma were later classified as CCOC [11].…”

Section: Discussionmentioning

confidence: 99%

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Clear Cell Odontogenic Carcinoma (CCOC): Mini-Review of Literature and Case Report of Mandibular Radiolucency in 17-year Girl

Jayapalan¹,

George²,

Noufal³

et al. 2016

Diagn Pathol Open

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A 17-year girl reported with painful right lower posterior teeth. Orthopantomogram showed unilocular radiolucency with scalloped non-sclerotic border at apical area of non-carious right mandibular molars and premolar. A provisional radiological diagnosis of ameloblastoma or odontogenic keratocyst was given. Histopathological examination revealed follicular areas of peripheral palisaded hyperchromatic basaloid cells and central round-polygonal clear cells. A diagnosis of clear cell odontogenic carcinoma (CCOC)-ameloblastomatous variant was made after assessing the provisional diagnoses. A nosological dilemma arose as many authors opined that the terms 'clear cell ameloblastoma' and 'clear cell odontogenic tumor' should be invalidated and CCOC should be the preferred diagnosis because of the reported aggressive nature of clear cell odontogenic neoplasms. The scientific literature gave variable biological behavior and prognosis with diverse therapeutic approaches leading to therapeutic dilemma in management of the case. The authors have attempted to resolve the diagnostic and therapeutic challenges by presenting the clinical, radiological and histological aspects of the case and discussing the differential diagnoses of clear cell lesions involving the maxillofacial region along with the therapeutic approaches and prognosis of CCOC.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Clear Cell Odontogenic Carcinoma (CCOC): Mini-Review of Literature and Case Report of Mandibular Radiolucency in 17-year Girl

Jayapalan¹,

George²,

Noufal³

et al. 2016

Diagn Pathol Open

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“…36,37 However, tooth mobility, displacement and nonvital teeth are most common signs present in central tumors of the jaws. 23,24 They include Malignant odontogenic tumors, 24,38 Osteosarcomas, 40 Ewings sarcoma, 41 Intraosseous muco epidermoid carcinomas, 42 Burkitts lymphoma, 43 Multiple myelomas. 28 Primary malignancies such as Squamous cell carcinoma and Large B cell lymphoma may also clinically present as peri implantitis.…”

Section: White Patch With Firm Consistency [Figure 2]mentioning

confidence: 99%

Warning Signs and Symptoms of Oral Cancer and its Differential Diagnosis

Muthu¹,

Vaishnavi²,

Ganapathy³

2018

JYP

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Oral Cancer (Oral Squamous Cell Carcinoma; OSCC) contributes to one of the important causes of mortality in human beings. These impending malignancies however may present clinically with warning signs and symptoms which is often neglected due to the lack of awareness in the population. Though there are developments in diagnosing early stage of oral cancer,the detection rate is continued to be minimal. Research proved a strong association between early diagnosis and better prognosis in these malignancies. Hence, knowledge regarding these warning indicators will certainly facilitate the clinicians to discover early cancer and provide an overall benefit pertaining to treatment in these patients.This review aims to highlight the early signs and symptoms of OSCC and their significance in improved prognosis of the patients. A Medline-PubMed search was conducted of the literature over the past years using the keywords: "oral squamous cell carcinoma" , "warning signs" , "Early symptom" , "clinical presentation" , "white lesion" , "ulcer" , "erythroplakia" , and "abnormal growth" . A total of 58 articles were reviewed, of which 11 were literature reviews, 15 were original studies and 32 were case reports. Appropriate Asssesment and analysis were performed to identify prompt warning signs and symptoms of OSCC.The key findings of all the early presentation were Eloborated with its clinical significance. In addition,this paper also helps to identify particular type of oral malignancies with their common clinical presentation reaching its emphasis based on the warning signs and symptoms.The importance of re-evaluation and biopsy to diagnose/eliminate malignant lesion in doubtful clinical situation is also highlighted.

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“…50 Despite its bland cytological features, the tumour exhibits extensive local infiltrative growth into the muscles and nerves. 51 This newer entity has been included in the 2017 WHO classification; however, metastasis has not been reported in any of the seven cases described to date. 2,51 Hence, further study of its biological behaviour is required to confirm its placement within the category of odontogenic carcinomas.…”

Section: 50mentioning

confidence: 99%

Controversies in Odontogenic Tumours: Review

Siwach

Joy

Tupkari

et al. 2017

SQUMJ

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Odontogenic tumours are lesions that occur solely within the oral cavity and are so named because of their origin from the odontogenic (i.e. tooth-forming) apparatus. Odontogenic tumours comprise a variety of lesions ranging from non-neoplastic tissue proliferations to benign or malignant neoplasms. However, controversies exist regarding the pathogenesis, categorisation and clinical and histological variations of these tumours. The recent 2017 World Health Organization classification of odontogenic tumours included new entities such as primordial odontogenic tumours, sclerosing odontogenic carcinomas and odontogenic carcinosarcomas, while eliminating several previously included entities like keratocystic odontogenic tumours and calcifying cystic odonogenic tumours. The aim of the present review article was to discuss controversies and recent concepts regarding odontogenic tumours so as to increase understanding of these lesions.

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Malignant Odontogenic Tumors: An Update on Selected Tumors

Cited by 34 publications

References 44 publications

Clear Cell Odontogenic Carcinoma (CCOC): Mini-Review of Literature and Case Report of Mandibular Radiolucency in 17-year Girl

Clear Cell Odontogenic Carcinoma (CCOC): Mini-Review of Literature and Case Report of Mandibular Radiolucency in 17-year Girl

Warning Signs and Symptoms of Oral Cancer and its Differential Diagnosis

Controversies in Odontogenic Tumours: Review

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