Malignant Odontogenic Tumors: A 22‐Year Experience

Goldenberg, David M.; Sciubba, James J.; Koch, Wayne M.; Tufano, Ralph P.

doi:10.1097/00005537-200410000-00018

Cited by 103 publications

(116 citation statements)

References 12 publications

(14 reference statements)

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“…How many arose specifically in KCOT was not specified. In another review of malignant odontogenic tumors, only 1 of 9 was a carcinoma arising in a keratocyst [23]. These tumors are more common in the mandible and are treated with segmental resection with selective neck dissection for the N0 neck or modified radical neck dissection if positive nodes are present.…”

Section: Discussionmentioning

confidence: 99%

Keratocystic Odontogenic Tumor (KCOT/OKC)—Clinical Guidelines for Resection

Warburton

Shihabi

Ord

2015

J. Maxillofac. Oral Surg.

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Purpose There is no clinical consensus for the treatment of Keratocystic Odontogenic Tumor (KCOT). KCOTs are regarded as benign aggressive tumors and resection is usually considered as a last option. We review the clinical indications for resection based on a case series. Methods This is a retrospective study of patients with KCOT treated in a single unit over 17 years. Eighty patients were identified, of which 12 (15 %) underwent resection. The remaining 68 patients were managed by enucleation and curettage, enucleation with peripheral ostectomy, or decompression with secondary enucleation. Data extracted includes gender, age, race, location, previous treatment for the lesion, surgery and outcome/ follow up. Results Twelve patients treated by resection were identified. The location in the ten benign resected KCOTs was either the mandibular ramus or the posterior maxilla. All mandibular KCOTs exhibited perforation of the lingual plate and involvement of the pterygoid musculature. Seven of the ten cases were recurrent KCOTs and three had no prior treatment. Two had malignant changes in the KCOT and were also resected. Conclusion The primary reason for resection of KCOT was involvement of the pterygoid muscles. The presence of malignant change was a separate indication for resection.

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Section: Discussionmentioning

confidence: 99%

Keratocystic Odontogenic Tumor (KCOT/OKC)—Clinical Guidelines for Resection

Warburton

Shihabi

Ord

2015

J. Maxillofac. Oral Surg.

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“…Necrosis and overt invasion at the periphery can be difficult to find or demonstrate and borderline malignant appearances cause significant problems in diagnosis. In one review of 20 malignant odontogenic tumors, only 9 were accepted as truly malignant [4]. The criteria given in the classification for ameloblastic carcinoma are stringent and comprehensive, but do not address the difficulty of borderline lesions where a decision on malignancy can often be facilitated with radiological support.…”

Section: Malignant Odontogenic Tumorsmentioning

confidence: 99%

Odontogenic Tumors, WHO 2005: Where Do We Go from Here?

Wright

Odell

Speight

et al. 2014

Head and Neck Pathol

104

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“…Ameloblastoma, a locally aggressive tumour of odontogenic origin, constitutes only 1% of all oral tumours [1][2][3][4][5][6]. Clinically, it is painless and slow growing lesion, but behaves as invasive recurring tumours in spite of its benign histological appearance [1,2].…”

Section: Introductionmentioning

confidence: 99%

Adenomatoid Ameloblastoma in the Mandible and Maxilla: Report of a Case

Turğut

Ünsal

Özkara

2011

Indian J Otolaryngol Head Neck Surg

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Ameloblastoma is an infrequent odontogenic neoplasm located in the mandible and/or infratemporal fossa extending into the maxilla. The authors report a patient who underwent a total of five operative interventions for recurrent lesions involving mandible and infratemporal fossa at other institutions before admission to our hospital. Radiographic imaging in our case demonstrated a solid/multicystic recurrent lesion of the right infratemporal fossa extending into the maxilla. Gross total excision of the tumour was done and the postoperative course was uneventful. In any case with a tumour located in this region, it is important to be aware of this condition because this lesion is unusual but serious pathology as illustrated in this report.

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Malignant Odontogenic Tumors: A 22‐Year Experience

Abstract: Malignant odontogenic tumors are rare. They require a multidisciplinary team to determine proper treatment. Long-term surveillance is mandatory and is accomplished by routine physical examinations, along with serial radiographic imaging.

Cited by 103 publications

References 12 publications

Keratocystic Odontogenic Tumor (KCOT/OKC)—Clinical Guidelines for Resection

Keratocystic Odontogenic Tumor (KCOT/OKC)—Clinical Guidelines for Resection

Odontogenic Tumors, WHO 2005: Where Do We Go from Here?

Adenomatoid Ameloblastoma in the Mandible and Maxilla: Report of a Case

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