Malignant neurilemmoma of parotid gland

Laurian, N.; Zohar, Yuval

doi:10.1017/s0022215100073011

Cited by 4 publications

(6 citation statements)

References 16 publications

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“…found that 35% (n=62) of their patients with MPNST had a history of Neurofibromatosis I [20], neither our nor the 9 prior cases of MPSNT arising from the parotid gland have indicated a history of this genetic condition [3][4][5][6][7][8][9][10][11].…”

Section: Accepted Manuscriptcontrasting

confidence: 56%

“…A recent meta-analysis of 1800 cases MPNST found a five year survival rate of 44% [20]. Of the reported cases of parotid MPNST with sufficient follow-up, only 3 of 7 patients survived to one year [3][4][5][6]8,9,11]. While our patient did not undergo adjuvant chemotherapy and radiotherapy, he is still alive 12 years post-procedure.…”

Section: Accepted Manuscriptmentioning

confidence: 66%

“…Surgical resection usually yields excellent results in the management of these lesions [13,22,24] MPNST arising from the parotid gland have presented as both tender [6,7,[9][10][11] and non-tender [3][4][5]8] masses which have grown slowly over the course of 3-12 months, but can progress in a more accelerated time frame [6]. Of the 9 cases within the literature, only one has shown facial nerve palsy at the time of presentation [6].…”

Section: Accepted Manuscriptmentioning

confidence: 99%

“…A single institution retrospective analysis by Cho et al found that neurofibromas and schwannoma comprised 0.2% (n=1) and 1.1% (n=6) respectively of 527 mesenchymal tumors found in salivary glands [1]. Of the 22 neurofibromas [2], 9 [3][4][5][6][7][8][9][10][11] MPSNT, and approximately 150 schwannomas [12][13][14][15][16][17][18][19][20][21][22] in the literature that have been found to arise in the salivary gland, the vast majority have been reported as single case reports or small series [13].…”

Section: Introductionmentioning

confidence: 99%

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Peripheral nerve sheath tumors arising in salivary glands: A clinicopathologic study

Guraya

Prayson

2016

Annals of Diagnostic Pathology

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Section: Accepted Manuscriptcontrasting

confidence: 56%

Section: Accepted Manuscriptmentioning

confidence: 66%

Section: Accepted Manuscriptmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Peripheral nerve sheath tumors arising in salivary glands: A clinicopathologic study

Guraya

Prayson

2016

Annals of Diagnostic Pathology

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“…Although this in itself may cause a facial nerve paralysis as other authors have noted, 3,4 the paralysis is usually temporary. A tissue diagnosis reassures the surgeon and the patient that the correct diagnosis was made and rules out the possibility of a malignant schwannoma, which can mimic a benign schwannoma 19 …”

Section: Discussionmentioning

confidence: 99%

Intraparotid Facial Nerve Schwannoma: Diagnosis and Management

Caughey¹,

May²,

Schaitkin³

2004

Otolaryngol.--head neck surg.

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Intraparotid facial nerve schwannoma: management options

Fyrmpas

Konstantinidis

Hatzibougias

et al. 2007

Eur Arch Otorhinolaryngol

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Intraparotid facial nerve schwannoma (FNS) is a very rare, benign tumour mimicking pleomorphic adenoma. Resection of this slow growing tumour may result in unnecessary facial nerve paralysis. The aim of this study is to present results of facial nerve schwannoma treatment at our institution and proposes a management plan. This is a retrospective case series of four patients, three male and one female with a mean age of 47.7 years who presented with a long-standing, asymptomatic parotid swelling. Two patients had facial weakness and underwent superficial parotidectomy, resection of tumour and facial nerve repair with a free graft from the greater auricular nerve. Two patients underwent biopsy without tumour resection. All tumours were confirmed histologically as facial nerve schwannomas. The mean follow up period was 3.5 years. Patients with resection of facial nerve schwannoma had a postoperative House Brackmann grade III and IV. Patients with biopsy had normal postoperative facial nerve function and the tumour did not grow significantly. No adverse effects or recurrence were reported. There is no preoperative diagnostic modality that can identify facial nerve schwannoma with certainty. Difficulty in locating the facial nerve intraoperatively raises suspicion of a neurogenous tumour of the facial nerve and this may prevent unnecessary damage to the nerve. Not every facial nerve schwannoma should be resected. This decision is based on (a) the extent of tumour (b) preoperative facial nerve function (c) best results achieved with nerve repair and (d) patient's preferences. Large tumours with extension into the mastoid cavity or encroachment of sensitive structures and preoperative facial weakness are indications for surgical intervention. In most other cases, biopsy and observation suffices.

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Malignant neurilemmoma of parotid gland

Cited by 4 publications

References 16 publications

Peripheral nerve sheath tumors arising in salivary glands: A clinicopathologic study

Peripheral nerve sheath tumors arising in salivary glands: A clinicopathologic study

Intraparotid Facial Nerve Schwannoma: Diagnosis and Management

Intraparotid facial nerve schwannoma: management options

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