Malignant melanoma on a thermal burn scar

Lee, Han Byul; Han, So Eun; Chang, Lan Sook; Lee, Soo Hyang

doi:10.7181/acfs.2018.02103

Cited by 7 publications

(7 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several reports about melanoma formation following a single injury of the skin or arising from thermal burn scar can be found (Akiyama et al, 1997 ; Alconchel et al, 1997 ; Delaunay et al, 1991 ; Gellin & Epstein, 1975 ; Ikeda et al, 1995 ; Kaskel et al, 2000 ; Lee et al, 2019 ; Muhlemann et al, 1982 ; Nancarrow, 1979 ; Stilwell & Sclare, 1980 ). More recently, a retrospective standardized questionnaire was administered to 369 patients affected by melanoma in order to detect a possible association between a single or recurrent traumatic event and melanoma characteristics.…”

Section: Discussionmentioning

confidence: 99%

Chronic mechanical trauma/irritation and oral carcinoma: A systematic review showing low evidence to support an association

et al. 2021

View full text Add to dashboard Cite

Oral squamous cell carcinoma (OSCC) is the most frequent malignant neoplasia of the oral cavity.Several risk factors have been associated with the development of OSCC; first of all, smoked or chewed tobacco (with or without betel/areca nut) as well as alcohol consumption are currently considered the two most important risk factors implicated in the aetiology of OSCC (Jemal et al., 2011).High risk oncogenic human papillomaviruses (HPV) are also associated with oropharyngeal squamous cell carcinoma, with increasing incidence in developed countries (Gillison et al., 2015).

show abstract

Section: Discussionmentioning

confidence: 99%

Chronic mechanical trauma/irritation and oral carcinoma: A systematic review showing low evidence to support an association

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The exact cause of melanoma is not yet understood, but there are certain factors that may initiate and promote its development: ultraviolet (UV) radiation, indoor tanning [ 8 , 9 , 10 ], prolonged sun exposure/sunburn [ 11 ], burn scars [ 12 , 13 , 14 ], pesticides, genetic factors/heredity, geographical location, skin phototype, immunosuppression, hormonal changes, a high number of nevi, neuroendocrine factors, stress, depression [ 15 ], trauma, low socioeconomic status, non-melanoma skin cancers, autoimmune diseases, viral infections, biological/cytologic factors, smoking/alcohol, medicines, gender (melanoma has a higher incidence in men [ 16 , 17 , 18 , 19 , 20 ]), etc. [ 1 , 21 , 22 , 23 ].…”

Section: Resultsmentioning

confidence: 99%

Review: The Key Factors to Melanomagenesis

Mihulecea

Rotaru

2023

Life

View full text Add to dashboard Cite

Melanoma is the most dangerous form of skin cancer that develops from the malignant transformation of the melanocytes located in the basal layer of the epidermis (cutaneous melanoma). Melanocytes may also be found in the meninges, eyes, ears, gastrointestinal tract, genito-urinary system, or other mucosal surfaces (mucosal melanoma). Melanoma is caused by an uncontrolled proliferation of melanocytes, that at first may form a benign lesion (nevogenesis), but in time, it may transition to melanoma, determining what it is named, melanomagenesis. Some tumors may appear spontaneously (de novo melanoma) or on preexisting lesions (nevus-associated melanoma). The exact cause of melanoma may not be fully understood yet, but there are some factors that initiate and promote this malignant process. This study aims to provide a summary of the latest articles regarding the key factors that may lead to melanomagenesis. The secondary objectives are to reveal the relationship between nevi and melanoma, to understand the cause of “de novo” and “nevus-associated melanoma” and highlight the differences between these subtypes.

show abstract

“…There are, however, other conditions including traumatic wounds, venous ulcers, sinuses of osteomyelitis, pressure ulcers, radiation dermatitis, stings, bites and hidradenitis suppurativa 3. Four types of cancers are possible in a burn scar squamous cell carcinoma (Marjolijn’s ulcer),2 basal cell carcinoma,4 malignant melanoma (rare)5 and undifferentiated pleomorphic sarcoma (extremely rare and can have multiple foci) 6. There are only four reports in literature on the combination of the more than one type of cancer but no reports of any subtype in combination with undifferentiated pleomorphic sarcoma.…”

Section: Discussionmentioning

confidence: 99%

Synchronous carcinoma and sarcoma in a burn scar: a treatment conundrum

Thejashwini,

Pai

2024

BMJ Case Rep

View full text Add to dashboard Cite

Marjolijn’s ulcer is a malignant ulcer in a burn scar. Types of malignancy are squamous cell carcinoma, basal cell carcinoma and malignant melanoma. Soft tissue sarcoma case reports indicate only one type of cancer. We present a patient in her 60s with a 10-year-old burn scar developing a biopsy-proven squamous cell carcinoma on the lateral aspect of the left thigh with metastatic superficial inguinal node. A wide excision and grafting of ulcer with ilioinguinal dissection done on left side. On the 12th postoperative day 2, subcutaneous swellings adjacent to the grafted area developed, on biopsy revealed to be pleomorphic sarcoma. PET CT scan revealed tumour deposits in the muscles of the left lower limb, liver and lung. There are no case reports of synchronous carcinoma and sarcoma in a burn scar. The case is reported for its rarity and the decision-making dilemma.

show abstract

Malignant melanoma on a thermal burn scar

Cited by 7 publications

References 10 publications

Chronic mechanical trauma/irritation and oral carcinoma: A systematic review showing low evidence to support an association

Chronic mechanical trauma/irritation and oral carcinoma: A systematic review showing low evidence to support an association

Review: The Key Factors to Melanomagenesis

Synchronous carcinoma and sarcoma in a burn scar: a treatment conundrum

Contact Info

Product

Resources

About