Malignant Lymphoproliferative Disorders Extending into the Orbit from the Paranasal Sinuses

Abstract

Presenting symptoms of malignant orbital lymphoproliferative disorders extending from the paranasal sinuses include mass effect occasionally with infiltrative and inflammatory characteristics accompanied by symptoms of sinus disease. On imaging, a soft tissue mass in the sinuses and orbit with bone destruction is commonly seen. Biopsy is essential for conclusive diagnosis. Treatment should be initiated promptly as local symptoms are frequently relieved and survival is possible, especially in cases of NHL.

Paranasal sinus lymphoma: Retrospective review with focus on clinical features, histopathology, prognosis, and relationship to systemic lymphoma

“…Because systemic lymphoma is a common malignancy, review of the literature reveals much preexisting research into its diagnosis, staging, management, and prognosis. Furthermore, lymphoma's common secondary manifestations, such as orbital and adnexal lymphoma, leave the literature concentrated with studies showing their particular prognoses and rates of systemic spread . On the other hand, because of sinonasal lymphoma's rarity, there have been limited attempts to examine the relationship between localized paranasal sinus lymphoma and systemic disease .…”

Diffuse large B‐cell lymphoma and mantle cell lymphoma of the ocular adnexal region, and lymphoma of the lacrimal gland: An investigation of clinical and histopathological features

“…Diffuse large B-cell lymphoma spreads by tissue destruction in some cases (Peleg et al 2009). In the present study, only one patient presented with a destructive bone lesion involving the lower orbital floor (maxillary bone).…”