Malignant lymphoma with tumor thrombus in the portal venous system

Abstract

We report a case of malignant lymphoma presenting with tumor thrombus of the portal venous system. Computed tomography showed a mass in the portal vein and mesenteric lymphadenopathy. Filling defects in the dilated portal vein also were identified by angiography. This type of the lymphoma is extremely rare, but it should be considered in the differential diagnosis of portal vein thrombus.

A Rare Presentation of Non-Hodgkin’s Lymphoma Presenting With Bleeding Esophageal Varices Secondary to a Malignant Portal Vein Tumor Thrombosis

“…This makes our case the eighth reported presentation of NHL-associated PVTT in medical literature, and the fifth specifically associated with DLBCL. Many of these documented cases of NHL PVTT have had great success with CHOP chemotherapy, alone, resulting in PVTT resolution [4,5,7,8]. One of the earliest cases of NHL PVTT from 1996 documented by Irie and colleagues reported no specific patient outcomes [9].…”

“…This case describes an unusual etiology of esophageal variceal bleeding secondary to non-cirrhotic portal hypertension from an extensive PVTT caused by an NHL malignancy surrounding the celiac trunk. Current medical literature yields only seven previously reported cases of NHL-associated PVTT, of which four were specifically DLBCL [ 4 - 10 ]. This makes our case the eighth reported presentation of NHL-associated PVTT in medical literature, and the fifth specifically associated with DLBCL.…”

A case of acinar cell carcinoma of the pancreas that formed extensive tumor thrombus of the portal vein

“…Only one case of acinar cell carcinoma has been reported so far [15] (Table 1). Although tumor thrombosis in the portal venous system is rarely recognized in patients with malignant tumors except for HCC, in addition to these pancreatic tumors, a few exceptional malignancies such as gastric cancer [16][17][18][19][20][21][22][23][24], colorectal cancer [4,23,[25][26][27][28][29][30][31], gallbladder cancer [32], renal cancer [33], malignant lymphoma [34][35][36], and malignant melanoma [37] have been reported to develop portal tumor thrombus.…”

Diffuse Large B-cell Lymphoma with Massive Portal Vein Tumor Thrombosis in a Patient with Alcoholic Cirrhosis: A Case Report and Literature Review

“…L i t e r a t u r e Re v i e w o f Ma l i g n a n t L y mp h o ma wi t h P VT T Ab b r e v i a t i o n s , S R : s u r g i c a l r e s e c t i o n , C T: c h e mo t h e r a p y , NA: n o t a v a i l a b l e , C R : c o mp l e t e r e s p o n s e (9 (2). Two cases received combined chemotherapies (4,5), and one case underwent both surgical resection and combined chemotherapy (3) (11)(12)(13). Primary lymphoma of the spermatic cord is extremely rare and only a small number of cases have been reported to date (11,12).…”