Malignant lymphoma and nephrotic syndrome

Pleural Mesothelioma and Membranous Nephropathy

“…Tumor-related antigens or antibodies against these antigens have been identified in glomerular deposits in several cases of tumor-associated MGN [1, 14, 17]. Immunopathologic studies and reviews of electron microscopy findings in these patients also suggest an immune complex pathogenesis [1, 14, 17, 18]. …”

Membranous nephropathy associated with ovarian tumour in a young girl: recovery after removal

“…In contrast, no CEA was detected in renal biopsies of patients having nephrotic syndrome and carcinoma [21]. Other antigens have been involved in the pathogenesis of tumours associated with membranous nephropathy, such as desoxyribonucleic antigen liberated by tumoural necrosis [8] and viral antigens especially oncogene virus [9]. In other studies it was suggested that the tumour antigen in renal cell carcinoma was similar to renal tubular epithelium [18].…”

The association of non-Hodgkin's lymphoma with glomerulonephritis

“…From the group of patients dealt with in our review, only one had circulating immune complexes and cryoglobulins were detected in two. Finally, it is possible that the association between neoplasms and GN is a coincidence, with independent evolution presented in some cases (Hyman et al, 1973: Banks et al, 1984. However, the discovery of a greater incidence of neoplasms in some types of GN (Lee et al, 1966;Gluck et al, 1973;Biava et al, 1984;Row et al, 1975) would lend support to a causal relationship.…”