Malignant Hypertension: Clinical Manifestations of 7 Cases

Steinegger, Ken; Bergin, Ciara; Guex-Crosier, Yan

doi:10.1055/s-0034-1396333

Cited by 10 publications

(3 citation statements)

References 9 publications

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“…Malignant hypertension is a hypertensive urgency characterized by grade III/IV retinopathy and widespread endothelial damage [13]. Steinegger et al [14] investigated the types of symptoms and ocular lesions observed with ocular fundus examination, ocular fundus photography, fluorescein angiography and optical coherence tomography in a small case series of 7 patients with malignant hypertension.thay found that the Median systolic blood pressure (BP) was 205 mmHg±21.…”

Section: Discussionmentioning

confidence: 99%

Study of clinical and ophthalmic menefestations of malignant hypertension

Telgote

Singh²

2015

Int J Med Res Rev

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Introduction: Malignant hypertension is high blood pressure that comes suddenly and quickly. We attempted to review the clinical and fundus findings in patients with malignant hypertension (MHT). The lower (diastolic) blood pressure reading which is normally less than 80 mmHg, is often above 130 mmHg (240/140mmHg). Malignant hypertension may present with retinopathy, choroidopathy, and optic neuropathy. Optical coherence tomography is a relatively new imaging technique for evaluating retinal thickness and the location of pathologyin patients with malignant hypertension. Material and Methods: A retrospective observational study was carried in the department of ophthalmology comprising two groups based on history of history of hypertension (group1)and no history of hypertension (group2). The charts and fundus photographs of patients with hypertensive retinopathy from 2010 to 2015 was studied. Data of patients were included when their color photographs of the fundus were judged to indicate hypertensive retinopathy grade III or IV. There had to have been at least 1 high blood pressure reading recorded in the chart during the period when the symptoms occurred. Results: Twenty patients were included in our study. Patients were divided into 2 groups according to whether or not they had a history ofhypertension. Group 1 included 8 patients with no hypertension history, while group 2 included 12 patients with a known hypertension history. In group 1, Malignant hypertension was diagnosed by an ophthalmologist in 8 patients, in which 4:4 M:F ratio and In group 2 , 12 patients of malignant hypertension, in which M:F ratio being 3:9.There were no significant differences in age, or systolic and diastolic blood pressures. There were more complications such as renal failure and stroke in group 2 patients. Conclusion: Funduscopy has decisive significance in the diagnosis and monitoring of MHT. In order to accurately diagnose and achieve early control of this critical condition, a detailed fundus examination and blood pressure monitoring are mandatory.

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Section: Discussionmentioning

confidence: 99%

Study of clinical and ophthalmic menefestations of malignant hypertension

Telgote

Singh²

2015

Int J Med Res Rev

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“…Thus, retinal fundoscopy should be performed in all patients presenting with severely increased blood pressure on examination [2]. It is due to the fact that typical retinal changes are dynamic, start to regress immediately upon the implementation of the antihypertensive treatment and do not persist for longer than 2-3 months [2,15]. Although in some cases, when patients present with extreme signs of blood pressure elevation, such as hypertensive encephalopathy and MHT is suspected, Grade 3-4 ocular changes might be absent during their initial examination [16].…”

Section: Diagnostic Difficultiesmentioning

confidence: 99%

Malignant hypertension: does this still exist?

et al. 2019

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“…Tryfon и соавт. [27] отмечают, что она представляет собой опасное для жизни состояние, вызванное резким повышением системного артериального давления. Острая гипертония может вызывать ряд изменений на глазном дне [22], включая ретинопатию, хориопатию и нейропатию, что приводит к серьезному ухудшению зрения.…”

Section: гипертоническая ретинопатия при злокачественной артериальнойunclassified

Modern Aspects of Hypertensive Angioretinopathy

Lk¹,

Воробьева²,

Dgebuadze³

2019

Oftalʹmologiâ

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This literature review is devoted to modern problems of hypertensive retinopathy with arterial hypertension, as well as hypertensive retinopathy in combination diseases. The latest world studies were analyzed. Particular attention is paid to the clinical disease characteristics at the present stage with the analysis of the arterio-venous ratio, optic nerve edema (with high blood pressure figures) using an automated system, vector analysis, suggesting a new arteriovenous classification, called Web Integration (Wivern). The modern pathogenesis of hypertensive retinopathy, namely the ratio of proangiogenic and anti-angiogenic factors, the role of inflammation (C-reactive protein), the role of endothelin-1, endostatin, interleukin-8 (IL-8), and the main fibroblast growth factor (bFGF ), angiogenin and uric acid. The special importance of fundus registration is reflected with the help of the newest equipment at high figures of arterial pressure in patients with hypertensive retinopathy. It is known that according to the World Health Organization (WHO), mortality rate from cardiovascular diseases is 31 %. Hypertension is the main risk factor for coronary heart disease, myocardial infarction, heart failure, stroke, kidney disease and early death. Questions of eye blood flow in hypertensive angioretinopathy in patients with arterial hypertension (AH) are covered. Hypertensive retinopathy (HR) is a retinal disease that is caused by a prolonged increase blood pressure (BP) and leads to a decrease in vision. The data of pathophysiology are analyzed (arterial hypertension (AH) leads to thickening of the vessels of the inner membrane (intima), to thickening of the medial membrane (media) — hyperplasia of the muscular tissue followed by hyaline degeneration with the development of sclerotic changes). The questions of modern diagnostics with retinal morphological status evaluation (OCT), detection of eye fundus condition with newest fundus camers, pathogenetic aspects are discussed. This review will help to prevent the development of more severe forms of hypertensive retinopathy. This information will allow us to identify the most significant indicators in the early diagnosis of hypertension angioretinopathy.

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Malignant Hypertension: Clinical Manifestations of 7 Cases

Abstract: The association of multiple lesions strongly suggests malignant hypertension. However even in cases with only one lesion malignant hypertension should be kept in mind.

Cited by 10 publications

References 9 publications

Study of clinical and ophthalmic menefestations of malignant hypertension

Study of clinical and ophthalmic menefestations of malignant hypertension

Malignant hypertension: does this still exist?

Modern Aspects of Hypertensive Angioretinopathy

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