Malignant glaucoma after XEN45 implant

Montolío-Marzo, Santiago; Lanzagorta-Aresti, Aitor; Cabrera, JL; Muñoz, Edgar; Ludeña, J.V. Piá; Pozo, E. Palacios

doi:10.1016/j.oftale.2018.10.014

Cited by 9 publications

(5 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…MIGS are known to have a lower complication rate than glaucoma filtration surgery, though they are not free from the risk of malignant glaucoma development [ 19 ]. Schlenker et al reported four cases of malignant glaucoma after ab interno gelatin microstent (XENGelStent, Allergan, Inc., USA) implantation [ 20 ], and Montolío Marzo et al reported a case of malignant glaucoma following phacoemulsification and XEN Gel Stent 45 implantation [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

Malignant glaucoma following gonioscopy-assisted transluminal trabeculotomy: a case report

et al. 2022

View full text Add to dashboard Cite

Background To report a case of malignant glaucoma that developed after gonioscopy-assisted transluminal trabeculotomy (GATT). Case presentation An 85-year-old male pseudophakic patient affected by pseudoexfoliative glaucoma (PEXG), unresponsive to medical glaucoma treatment, underwent uneventful GATT surgery. On the first day after surgery, the eye showed a shallow central and peripheral anterior chamber (AC) with a raised intraocular pressure (IOP) measured at 55 mmHg. Optical coherence tomography and ultrasound biomicroscopy confirmed the diagnosis of malignant glaucoma. Laser iridotomy, posterior capsulotomy and hyaloidotomy were performed, and the patient was treated with atropine sulphate 1%, maximum topical and systemic ocular hypotensive drugs with no improvement in the IOP. Subsequently, the patient underwent pars plana anterior vitrectomy, resulting in deepening of the AC with opening of the iridocorneal angle and decrease of the IOP. No further postoperative complications were recorded, and the IOP remained controlled 12 months after surgery without antiglaucoma medications. Conclusions Despite the minimally invasive profile of GATT, malignant glaucoma may develop after this procedure. Early recognition and prompt treatment are mandatory for preventing permanent visual loss.

show abstract

Section: Discussionmentioning

confidence: 99%

Malignant glaucoma following gonioscopy-assisted transluminal trabeculotomy: a case report

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Off-label ab externo implantation allowed greater control of the distal end's placement in the subconjunctival space which, in our cases, led to better IOP control. Previous cases have described ciliovitreal block following ab interno XEN placement, but this is the first, to our knowledge, case of ciliovitreal block occurring after ab externo XEN tation [17][18][19].…”

Section: Discussionmentioning

confidence: 99%

Early Ciliovitreal Block following Ab Externo XEN Gel Implantation

Ning

2023

Case Reports in Ophthalmological Medicine

View full text Add to dashboard Cite

Purpose. To report a case of ciliovitreal block following ab externo implantation of a XEN gel stent for glaucoma. Methods. Case report. Results. An 84-year-old African American male underwent ab externo implantation of a XEN gel stent for elevated intraocular pressure. Several days after the surgery, the patient developed severe eye pain and reduced vision. Examination revealed ciliovitreal block (also called aqueous misdirection or malignant glaucoma) which was unresponsive to medical and laser treatment. Pars plana vitrectomy with anterior and posterior synechialysis and anterior chamber reformation were performed. The ciliovitreal block was resolved, and intraocular pressure brought to acceptable levels, but vision in that eye remained poor, likely due to the period of elevated pressure prior to treatment. Conclusion. Ciliovitreal block is a rare postsurgical (typically) form of secondary angle closure characterized by narrow or flat central and peripheral anterior chamber, anterior displacement of the lens-iris diaphragm, anterior rotation of ciliary processes, and (usually) elevated intraocular pressure. To our knowledge, this is the first reported case of ciliovitreal block occurring after ab externo XEN implantation. Early diagnosis and treatment are essential for preventing vision loss.

show abstract

“…While effective, it is not immune to major adverse effects in some circumstances. 24 A rare delayed consequence of cataract surgery is the development of malignant glaucoma. A growing tendency toward myopia can be an indicator of this process early on.…”

Section: Discussionmentioning

confidence: 99%