Malignant Chondroblastoma of the Os Calcis

Elek, E; Grimer, R. J.; Mangham, D. C.; Davies, A. M.; Carter, Simon R.; Tillman, R. M.

doi:10.1080/13577149878154

Cited by 20 publications

(19 citation statements)

References 11 publications

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“…Recurrence rates of 10-40% have been described [1,5,9,13]. There have been rare reports of seeding into soft tissues locally, and of pulmonary metastasis in about 1% of cases [12,14]. Growth disturbance rates and growth deformities are not widely published in the available literature.…”

Section: Discussionmentioning

confidence: 97%

Chondroblastoma of the femoral head: management and outcome

Strong

Grimer

Carter

et al. 2009

International Orthopaedics (SICOT)

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Chondroblastoma of the femoral head presents particular problems in treatment because the tumour is surrounded by articular cartilage on one side and epiphyseal plate on the other. Ten patients underwent treatment for a chondroblastoma involving the proximal femoral capital epiphysis. The patients were aged between eight and 19 years and in four the epiphysis was not yet fused. Five had curettage via a drill hole created up the femoral neck, of whom two developed local recurrence. Five had a direct approach to the chondroblastoma through the femoral neck, and there were no local recurrences in this group. Both patients with local recurrence were under 14 years of ageone was cured by a direct approach through the neck of the femur and the other by lifting a trap door of articular cartilage. Apart from one patient with a temporary leg length discrepancy, there were no other complications. We conclude that a direct approach is likely to lead to the best outcome for this rare condition.

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Section: Discussionmentioning

confidence: 97%

Chondroblastoma of the femoral head: management and outcome

Strong

Grimer

Carter

et al. 2009

International Orthopaedics (SICOT)

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“…In pulmonary metastasis, thoracotomy has produced apparent long-term cures, while in other sites the lesions have remained static following simple biopsy [7,25,27]. The benefit from chemotherapy is debatable [6,25,27]. Some authors recommend that any patient with a local recurrence should be screened for metastases [13].…”

Section: Discussionmentioning

confidence: 99%

“…Metastasis only followed local recurrence in association with malignant transformation at the primary site [6,27]. Patients usually survive several years with metastatic lesions.…”

Section: Discussionmentioning

confidence: 99%

Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery

Mashhour

Rahman

2013

International Orthopaedics (SICOT)

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Purpose Various methods for the treatment of chondroblastoma of bone have been used including simple curettage, or combined with bone grafting, in addition to the use of adjuvant therapy. However, local recurrence still represents a challenge in the management of this aggressive tumour. This study focuses on evaluating the role of intraregional extended curettage together with the use of adjuvant cryotherapy and autogenous bone grafting in the treatment of benign chondroblastoma of bone aiming to decrease the recurrence rate. Methods All patients with chondroblastoma included in this study underwent intralesional extended curettage, adjuvant cryotherapy using liquid nitrogen, and autogenous iliac crest bone grafting. Follow up for healing of chondroblastoma lesions and detection of any local recurrence was assessed on clinical and radiological bases. The functional outcome was assessed by the Musculoskeletal Tumour Society scoring system. Results The mean follow-up period was 49 months. The average time for bone healing was 7.4 months. Our rate of local recurrence is 7.1 %. Two patients (14.3 %) developed physeal growth arrest. One patient had superficial skin sloughing (7.1 %). None of the cases had pathological fracture. The mean Musculoskeletal Tumour Society functional score was 92.7 %. Conclusion Chondroblastoma is an aggressive benign bone tumour with a high rate of recurrence. The use of high-speed burr combined with adjuvant intralesional cryotherapy and iliac crest autogenous bone grafting is a reliable method of treatment with a low rate of recurrence.

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“…There have been several reported cases of multifocal chondroblastoma, which were considered as multiple primary lesions (12,13). Aggressive chondroblastoma with pulmonary metastasis is considered to be 'malignant' chondroblastoma (14). The term 'aggressive' chondroblastoma has been applied from a clinical point of view rather than as a histopathological entity.…”

Section: Case Reportmentioning

confidence: 99%

Bone multicentric epithelioid hemangioendothelioma of the lower and upper extremities with pulmonary metastases: A case report

Zhang

2015

Oncology Letters

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Abstract. The present study reports a rare case of bone multicentric epithelioid hemangioendothelioma (EH) involving the upper and lower extremities simultaneously, with visceral involvement of the lung. Osteolytic lesions were first identified in the right distal femur and proximal tibia. Slight increased radionuclide uptake was observed in the right shoulder joint on bone scintigraphy, however, this was ignored, as no clinical symptoms were present. The pa tient was initially misdiagnosed with multifocal chondroblastoma, and an extra-articular curettage of lesions was performed in the proximal tibia and medial femoral condyle, which was filled with bone cement. The histopathological diagnosis was corrected post-operatively following immunohistochemical analysis, which indicated EH, and subsequently, an amputation of the right leg at thigh level was performed. In addition, multiple lytic lesions in the right shoulder joint and pulmonary metastases were identified on whole-body radiological examination. Radiotherapy was administered to the right shoulder joint, however, the patient re fused chemotherapy or further surgery. At 15 months after the initial surgery, the patient currently remains alive. This case indicates that an improved understanding with regard to the clinical features of this disease may prevent misdiagnosis and improve EH treatment.

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Malignant Chondroblastoma of the Os Calcis

Cited by 20 publications

References 11 publications

Chondroblastoma of the femoral head: management and outcome

Chondroblastoma of the femoral head: management and outcome

Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery

Bone multicentric epithelioid hemangioendothelioma of the lower and upper extremities with pulmonary metastases: A case report

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