Malignant blue nevus

Goldenhersh, Michael A.; Savin, Ronald C.; Barnhill, Raymond L.; Stenn, Kurt S.

doi:10.1016/s0190-9622(88)70227-3

Cited by 118 publications

(35 citation statements)

References 28 publications

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“…Patients with Mongolian spots or nevi of Ito or Ota [46] should undergo frequent clinical control because of the potential malignant transformation [47]. The tumor often presents clinically as a progressively enlarging or multinodular blue-black lesion [48]. The histological pattern is of fascicular dense collections of pigmented, pleomorphic spindle cells.…”

Section: Discussionmentioning

confidence: 99%

Large Agminated Cellular ‘Plaque-Type' Blue Nevus Surrounding the Ear: A Case and Review

Spring

Perrier

Erba³

et al. 2013

Dermatology

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Large or giant cellular blue nevi are usually congenital and represent a challenge for the physician. Close anatomic structures may be altered by the size of the moles. In this article, we report the case of an uncommon large, agminated, cellular blue nevus of the ‘plaque type' in a 42-year-old female. Due to the risks of malignant melanoma development on a large or giant blue nevus, we highlight the importance of proper histopathological diagnosis. Furthermore, because of the possibility that the nevus may invade the bone and cerebral tissues, we discuss the indication of a radiological diagnosis. The accurate correlation to clinical and histopathological findings and appropriate multidisciplinary management can save the lives of patients.

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Section: Discussionmentioning

confidence: 99%

Large Agminated Cellular ‘Plaque-Type' Blue Nevus Surrounding the Ear: A Case and Review

Spring

Perrier

Erba³

et al. 2013

Dermatology

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show abstract

“…"Benign" metastasis of CBN to regional lymph nodes is well documented [8,9], so that regional nodal involvement by nevus cells should not be considered evidence of MBN in the absence of other histopathologic evidence of malignancy. It may be difficult to distinguish between CBN and metastatic melanoma [2,11], however, as illustrated by the follow-ing report. This case is interesting because the nevus was extraordinarily large and located on the chest wall.…”

Section: Introductionmentioning

confidence: 99%

“…Blue nevi are uncommon benign pigmented lesions that usually occur on the buttocks, dorsum of the hands and feet, scalp, and face [1][2][3]. They are usually small, with an average diameter up to 2 cm [2,4].…”

Section: Introductionmentioning

confidence: 99%

“…They are usually small, with an average diameter up to 2 cm [2,4]. In rare cases large plaque type lesions may occur [5].…”

Section: Introductionmentioning

confidence: 99%

“…In rare cases large plaque type lesions may occur [5]. Malignant blue nevi (MBN) [2,4,6,7] are rare and present as an uncommon type of melanoma arising in the background of a cellular blue nevus (CBN) [3]. "Benign" metastasis of CBN to regional lymph nodes is well documented [8,9], so that regional nodal involvement by nevus cells should not be considered evidence of MBN in the absence of other histopathologic evidence of malignancy.…”

Section: Introductionmentioning

confidence: 99%

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