Malignancy

Tiwari, Jawahar L.; Terasaki, Paul I.

doi:10.1007/978-1-4613-8545-5_12

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2001

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“…There have been relatively few studies linking HLA and cancer. Early studies describe associations between DR antigens and thyroid cancer, renal cell cancer, Burkitt’s lymphoma, Kaposi’s sarcoma and nasopharyngeal carcinoma (38, 39), and more recently with cervical carcinoma (40–44), nasopharyngeal carcinoma (45) and Hodgkin’s disease (46). The HLA‐DQB1*03 alleles are implicated in susceptibility to cervical carcinoma in Europe (40, 41, 43), USA (42) and Japan (44) and, as with HCC and HBV, there is also a strong link with virus (47).…”

Section: Discussionmentioning

confidence: 99%