Malic acid production from thin stillage by Aspergillus species

West, Thomas P.

doi:10.1007/s10529-011-0720-7

Cited by 65 publications

(34 citation statements)

References 19 publications

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“…However, citric acid production is much stronger and more consistent in A. niger. In section Circumdati, the dominant small acid seems to be malic acid (Srivastava and Kamal 1980;West 2011), but most species in that section produce the small polyketide acid penicillic acid (Frisvad et al 2004a, b;Visagie et al 2014a, b, c), not produced by species in any other Aspergillus section. The main acid produced by A. fumigatus appear to be epoxysuccinic acid (Martin and Foster 1955), but in general species in the unrelated sections Nigri, Terrei and Cremei are the most efficient producers of small organic acids.…”

Section: Analogous Secondary Metabolites Are Produced In Different Sementioning

confidence: 99%

Chemodiversity in the genus Aspergillus

Frisvad

Larsen

2015

Appl Microbiol Biotechnol

111

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Isolates of Aspergillus species are able to produce a large number of secondary metabolites. The profiles of biosynthetic families of secondary metabolites are species specific, whereas individual secondary metabolite families can occur in other species, even those phylogenetically and ecologically unrelated to Aspergillus. Furthermore, there is a high degree of chemo-consistency from isolate to isolate in a species even though certain metabolite gene clusters are silenced in some isolates. Genome sequencing projects have shown that the diversity of secondary metabolites is much larger in each species than previously thought. The potential of finding even further new bioactive drug candidates in Aspergillus is evident, despite the fact that many secondary metabolites have already been structure elucidated and chemotaxonomic studies have shown that many new secondary metabolites have yet to be characterized. The genus Aspergillus is cladistically holophyletic but phenotypically polythetic and very diverse and is associated to quite different sexual states. Following the one fungus one name system, the genus Aspergillus is restricted to a holophyletic clade that include the morphologically different genera Aspergillus, Dichotomomyces, Phialosimplex, Polypaecilum and Cristaspora. Secondary metabolites common between the subgenera and sections of Aspergillus are surprisingly few, but many metabolites are common to a majority of species within the sections. We call small molecule extrolites in the same biosynthetic family isoextrolites. However, it appears that secondary metabolites from one Aspergillus section have analogous metabolites in other sections (here also called heteroisoextrolites). In this review, we give a genus-wide overview of secondary metabolite production in Aspergillus species. Extrolites appear to have evolved because of ecological challenges rather than being inherited from ancestral species, at least when comparing the species in the different sections of Aspergillus. Within the Aspergillus sections, secondary metabolite pathways seem to inherit from ancestral species, but the profiles of these secondary metabolites are shaped by the biotic and abiotic environment. We hypothesize that many new and unique section-specific small molecule extrolites in each of the Aspergillus will be discovered.

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Section: Analogous Secondary Metabolites Are Produced In Different Sementioning

confidence: 99%

Chemodiversity in the genus Aspergillus

Frisvad

Larsen

2015

Appl Microbiol Biotechnol

111

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“…The known malic acid-producing strains A. niger ATCC 9142, A. niger ATCC 10577 and A. niger ATCC 12846 were used in this study [5] and obtained from the American Type Culture Collection, Manassas, VA, USA. Each strain of Aspergillus was inoculated into 10 mL potato dextrose broth (Difco Laboratories, Inc., Detroit, MI, USA) using a loopful of fungal mycelium, and the culture was grown for 48 h at and 10% crude glycerol.…”

Section: Fungal Strains and Culture Conditionsmentioning

confidence: 99%

“…Each strain of Aspergillus was inoculated into 10 mL potato dextrose broth (Difco Laboratories, Inc., Detroit, MI, USA) using a loopful of fungal mycelium, and the culture was grown for 48 h at and 10% crude glycerol. The potassium carbonate was added as a neutralizing agent [5] , and its pH was adjusted to 6.0. The crude glycerol, obtained from a local soy biodiesel producer, contained 79% glycerol and 16% methyl esters of fatty acids, which was determined enzymatically and by chemical analysis [9] .…”

Section: Fungal Strains and Culture Conditionsmentioning

confidence: 99%

Fungal biotransformation of crude glycerol into malic acid

West

2015

Zeitschrift Für Naturforschung C

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Malic acid production from the biodiesel coproduct crude glycerol by Aspergillus niger ATCC 9142, ATCC 10577 and ATCC 12846 was observed to occur with the highest malic acid level acid being produced by A. niger ATCC 12846. Fungal biomass production from crude glycerol was similar, but ATCC 10577 produced the highest biomass. Fungal biotransformation of crude glycerol into the commercially valuable organic acid malic acid appeared feasible.

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“…Malic acid is an [17] organic acid with chemical formula of HO 2 CCH 2 CHOHCO 2 H. Methods to produce malic acid are described in many studies [21][22][23][24][25]. Lassila and Slone [26] investigated on malic acid diester surfactant in waterborne coating, inks, adhesive, Overview on Chemical-Based, Bio-based …fountain solution and agricultural applications.…”

Section: Natural-based Surfactantmentioning

confidence: 99%

Overview on Chemical-Based, Bio-based and Natural-Based Surfactants in EOR Applications

et al. 2015

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Energy consumption in the world is increasing every year while expanding technology trying to catch up with the demand of oil production. One of the technologies which has been widely used to enhance oil recovery is surfactant flooding. A variety of surfactants promote oil recovery are reviewed in this paper, with particular emphasis on the ability: (i) to lower the interfacial tension (ii) to adjust the pH and (iii) to stand the high salinity conditions of reservoirs. To date, surfactants studied in enhanced oil recovery applications can be categorized as chemical-based, bio-based and natural-based surfactants.

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Malic acid production from thin stillage by Aspergillus species

Cited by 65 publications

References 19 publications

Chemodiversity in the genus Aspergillus

Chemodiversity in the genus Aspergillus

Fungal biotransformation of crude glycerol into malic acid

Overview on Chemical-Based, Bio-based and Natural-Based Surfactants in EOR Applications

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