Male hypogonadism: Symptoms and treatment

Abstract

Male hypogonadism is a condition in which the body does not produce enough of the testosterone hormone; the hormone that plays a key role in masculine growth and development during puberty. There is a clear need to increase the awareness of hypogonadism throughout the medical profession, especially in primary care physicians who are usually the first port of call for the patient. Hypogonadism can significantly reduce the quality of life and has resulted in the loss of livelihood and separation of couples, leading to divorce. It is also important for doctors to recognize that testosterone is not just a sex hormone. There is an important research being published to demonstrate that testosterone may have key actions on metabolism, on the vasculature, and on brain function, in addition to its well-known effects on bone and body composition. This article has been used as an introduction for the need to develop sensitive and reliable assays for sex hormones and for symptoms and treatment of hypogonadism.

Obesity and male hypogonadism: Tales of a vicious cycle

“…Undoubtedly, hypogonadism among several other hormonal alterations are important mediators in this process. In addition to reduced libido and erectile dysfunction, hypogonadal men can also present variable degrees of impaired spermatogenesis . Therefore, despite all the previously described effects of male gonadal dysfunction, one of the most negative consequences is related to the reproductive potential and poor fertility outcomes.…”

“…In addition to reduced libido and erectile dysfunction, hypogonadal men can also present variable degrees of impaired spermatogenesis. 124 Therefore, despite all the previously described effects of male gonadal dysfunction, one of the most negative consequences is related to the reproductive potential and poor fertility outcomes. It is important to highlight that sperm quality and male fecundity potential are of a substantial public health importance, as decreased birth rates will eventually reflect in the progressive aging of the populations and lead to the inevitable steady increase of economic and social burden.…”

Особливості Мотиваційної Сфери Хворих Із Психоендокринним Синдромом На Тлі Гіпогонадизму

“…До складу ПС входять пси-хопатологічні феномени емоційної, вольової, інте-лектуальної та інстинктивної сфер. І хоча базова се-міотика психічних порушень є інваріантною, тобто основний психопатологічний симптомокомплекс завжди трапляється при будь-яких захворюваннях ендокринної системи, варто відзначити існування терапевтично значущих нозоспецифічних особли-востей ПС [2,3,7].…”

Testosterone, sex hormone-binding globulin and risk of cardiovascular events: A report from the Outcome Reduction with an Initial Glargine Intervention trial

“…Testosterone is a steroid hormone which plays an essential role in sexual and cognitive function as well as body development in men (8). The synthesis and release of testosterone into the blood from the Leydig cells in the testes is regulated by the hypothalamic-pituitarytesticular (HPT)-axis and secretion of luteinizing hormone (LH) ( Figure 2) (9).…”