Male Breast Cancer

Scheike, Ole

doi:10.1038/bjc.1973.185

Cited by 45 publications

(14 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The median age in the current study was 62, whereas it was 67 years in a prior study [1]. Several studies from Sweden and Denmark suggested that men tended to be older than women at the time of diagnosis [10,11]. In the current study, a hard, nontender mass was the main symptom of presentation.…”

Section: Discussionmentioning

confidence: 45%

Male Breast Cancer: 37-Year Data Study at a Single Experience Center in Turkey

et al. 2013

View full text Add to dashboard Cite

PurposeThe aim of this study is to evaluate the effects of prognostic factors on the overall survival (OS) and locoregional control (LC) among male breast cancer (MBC) patients treated at Cerrahpasa Medical School Hospital, along with a review of the related literature.MethodsThe data of 86 patients treated for MBC from 1973 to 2010 are retrospectively reviewed. Patient demographics and clinical information, including the date of diagnosis, treatment, clinical course, and the date and causes of death are routinely recorded.ResultsMedian follow-up was 66 months. Isolated local-regional recurrence and distant metastases were observed in 15 (17.4%) and 24 (34.1%) of the cases, respectively. The 5-year OS rate was 65.8%; the disease-free survival rate was 72.4%, and the LC rate was 89.7%. The prognostic factors influencing local relapse were the T stage (p=0.002) and the chest wall muscular invasion (p=0.027) in the univariate analysis. The prognostic factors influencing OS were the presence of a positive axillary lymph node (p=0.001) and the T stage (p=0.001) in the univariate analysis. The T stage (p=0.008) and node (N) stage (p=0.038) were significant prognostic factors for OS in the multivariate analyses. Also, the T stage (p=0.034) was found to be significant for LC.ConclusionWe found that only the tumor size and lymph node status were independent prognostic factors for survival. In addition, only the tumor size was an independent prognostic factor for locoregional relapse. Modified radical mastectomy and conservative surgical procedures had similar outcomes for LC.

show abstract

Section: Discussionmentioning

confidence: 45%

Male Breast Cancer: 37-Year Data Study at a Single Experience Center in Turkey

et al. 2013

View full text Add to dashboard Cite

show abstract

“…In the Middle Ages, more reports were published, and at the beginning of the 14th century the surgeon John of Arderne mentioned a priest of Colstone with a 2-year history of a slowly growing wound on the right nipple. In the 15th century, Franciscus Arcaeus and Ambroise Par6 mentioned again the existence of male breast cancer (Holleb et al, 1968;Meyskenset al, 1976;Satiani and Powell, 1978;Scheike, 1975). In the 19th century and in the first half of this century, some collective reviews and case-series were published (Satiani and Powell, 1978;Scheike, 1975;Treves and Holleb, 1955;Visfeidt and Scheike, 1973;Wainwright, 1927).…”

mentioning

confidence: 99%

“…In the 15th century, Franciscus Arcaeus and Ambroise Par6 mentioned again the existence of male breast cancer (Holleb et al, 1968;Meyskenset al, 1976;Satiani and Powell, 1978;Scheike, 1975). In the 19th century and in the first half of this century, some collective reviews and case-series were published (Satiani and Powell, 1978;Scheike, 1975;Treves and Holleb, 1955;Visfeidt and Scheike, 1973;Wainwright, 1927). The subject was reviewed by Crichlow (1972) and has recently become the object of renewed interest (Donegan, 1991).…”

mentioning

confidence: 99%

Review article: Epidemiology of male breast cancer. A meta‐analysis of published case‐control studies and discussion of selected aetiological factors

Sasco

Lowenfels

Jong

1993

Intl Journal of Cancer

339

206

View full text Add to dashboard Cite

Male breast cancer is a rare tumour in all parts of the world. About 1% of all breast cancers occur in men, but the male/female ratio is higher among black than among white populations. This effect can be seen in US cancer registries and even more markedly in African data. A positive correlation exists on a population scale between male breast cancer and prostate cancer. Seven case-control studies of male breast cancer are available, and a pooled analysis was conducted of the most commonly suspected risk factors. Male breast cancer appears to be associated with marital status: Mantel-Haenszel exposure odds ratio (EOR) for never married = 1.6; 95% confidence limits (CL) = 1.1, 2.3, religion (EOR for being Jewish = 2.1; 95% CL = 1.4, 3.2), previous breast pathology (EOR for positive history of benign breast disease = 2.7; 95% CL = 1.7, 4.2), gynaecomastia (EOR for positive history = 6.2, 95% CL = 3.4, 11.4), previous testicular pathology (EOR for positive history = 2.2; 95% CL = 1.5, 3.3), previous liver diseases (EOR for positive history = 1.6; 95% CL = 1.0, 2.4) and family history of breast cancer (EOR for first-degree relative with breast cancer = 2.5; 95% CL = 1.7, 3.7). No association is found with smoking history. Other potential risk factors such as reproductive history, education, occupation, anthropometric variables, association with various diseases, and specific exposures such as drug use, were not systematically evaluated in all studies and provide sometimes contradictory results, possibly due to small numbers of exposed subjects. Overall, the analytical epidemiology of male breast cancer presents similarities with the epidemiology of female breast cancer, with a potential role of factors related to hormonal status, relative hyperoestrogeny in men being potentially linked to increased risk of disease. Genetics may also play a role, with high risk linked to a familial history of breast cancer, and with a major risk in patients with Klinefelter's syndrome.

show abstract

“…Other epidemiologic and clinical studics havc found male breast cancer to be associated with an occupatiori in the armed forces. gynecomastia or benign breast disease, niurrips before the age of 20. orchitis or testicular injury, and presence of Klinefelter's syndrome (Schottenfeld et a !., 1963!., : Keller, 1967Scheike. 1975;Mabuchi et al., 1985).…”

mentioning

confidence: 99%

Incidence of male breast cancer in scandinavia, 1943–1982

Ewertz

Holmberg

Karjalainen

et al. 1989

Intl Journal of Cancer

View full text Add to dashboard Cite

Male breast cancer incidence was examined in a collaborative study of data from the cancer registries in Denmark, Finland, Norway and Sweden, comprising a total of 1,529 cases diagnosed from 1943 to 1982. Effects of age, time of diagnosis, birth cohort and country of residence were evaluated by using statistical models of the multiplicative Poisson type. The logarithm of incidence increased linearly with the logarithm of age and had a slope of about 5. In Denmark, male breast cancer incidence increased significantly with time, about 1% per year. No significant time effects were observed in the other countries. A significant effect of birth cohort appeared in Sweden only, but there was no particular trend in incidence by year of birth. In relation to Denmark, the risk of male breast cancer was lower in Sweden, Norway and Finland, the relative risk estimates with 95% confidence intervals being 0.82(0.72-0.94), 0.72(0.61-0.84) and 0.53(0.43-0.64) respectively. The variation within Scandinavia is similar for female breast cancer, pointing to common factors being involved in the etiology of breast cancer in both sexes.

show abstract

Male Breast Cancer

Cited by 45 publications

References 14 publications

Male Breast Cancer: 37-Year Data Study at a Single Experience Center in Turkey

Male Breast Cancer: 37-Year Data Study at a Single Experience Center in Turkey

Review article: Epidemiology of male breast cancer. A meta‐analysis of published case‐control studies and discussion of selected aetiological factors

Incidence of male breast cancer in scandinavia, 1943–1982

Contact Info

Product

Resources

About