Malassezia pachydermatis keratomycosis in a dog

Ledbetter, Eric C.; Starr, Jennifer K.

doi:10.1016/j.mmcr.2016.01.001

Cited by 10 publications

(10 citation statements)

References 18 publications

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“…keratomycosis [ 27 ]. There are more reports on other yeast species, namely, Malassezia pachydermatis associated with corneal ulcers [ 19 , 30 , 31 ]. We cannot conclude whether our findings reflect a higher incidence of these genera and their roles in severe corneal ulcer, as there is no established prevalence available.…”

Section: Discussionmentioning

confidence: 99%

Identification and antimicrobial susceptibility of microorganisms isolated from severe corneal ulcers of dogs in Thailand

Ekapopphan

Srisutthakarn

Moonarmart

et al. 2018

The Journal of Veterinary Medical Science

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This study aims to determine the microbiological profile and risk factors associated with antimicrobial-resistant bacteria in canine severe corneal ulcers. Thirty-two corneal and conjunctival swabs were collected from dogs with diagnosed severe corneal ulcers that presented to Prasu-Arthorn veterinary teaching hospital in Nakhon Pathom, Thailand from June 2015 to June 2016. Microorganisms were identified by means of genotypic and phenotypic approaches. Of 32 ulcers sampled, 26 (81.3%) yielded culturable microorganisms with 24 bacterial isolates and 7 fungal isolates. The most commonly isolated bacteria were Staphylococcus spp. (45.8%, 11/24) and Pseudomonas aeruginosa (20.8%, 5/24). Out of 11 staphylococcal isolates identified, 10 carried the mecA gene providing methicillin resistance. The extended-spectrum β-lactamase (ESBL) encoding genes blaCTX-M and blaVEB-1 were found in an Acinetobacter lwoffii isolate, and blaSHV was found in a P. aeruginosa isolate. Based on the Clinical Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoint criteria, minimum inhibitory concentrations values showed that all bacteria, except for staphylococci, were susceptible to current ophthalmic antibiotics. More than 50% of staphylococci were resistant to all generations of fluoroquinolones and fusidic acid. Chloramphenicol was highly active against staphylococci (81.3% susceptible). The width (P=0.02) and the depth (P=0.04) of ulcers predicted greater risk of yielding resistant bacteria. The identification of antimicrobial-resistant bacteria prompts practitioners to be prudent when choosing ophthalmic antibiotics for severe corneal ulcers.

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Section: Discussionmentioning

confidence: 99%

Identification and antimicrobial susceptibility of microorganisms isolated from severe corneal ulcers of dogs in Thailand

Ekapopphan

Srisutthakarn

Moonarmart

et al. 2018

The Journal of Veterinary Medical Science

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“…Another potential site of superficial Malassezia infection is the cornea. There are sparse reports of keratomycosis in humans and dogs associated with M. furfur and M. restricta in humans and M. pachydermatis in dogs [ 307 , 308 , 309 ]. Interestingly, one affected dog [ 309 ] and a human patient [ 308 ] both had diabetes mellitus and in all described cases immunomodulatory or antibiotic drugs were used.…”

Section: Superficial Malassezia -Associated Diseas...mentioning

confidence: 99%

“…There are sparse reports of keratomycosis in humans and dogs associated with M. furfur and M. restricta in humans and M. pachydermatis in dogs [ 307 , 308 , 309 ]. Interestingly, one affected dog [ 309 ] and a human patient [ 308 ] both had diabetes mellitus and in all described cases immunomodulatory or antibiotic drugs were used. These predisposing factors could have facilitated Malassezia species overgrowth.…”

Section: Superficial Malassezia -Associated Diseas...mentioning

confidence: 99%

Malassezia: Zoonotic Implications, Parallels and Differences in Colonization and Disease in Humans and Animals

Hobi

Cafarchia

Romano

et al. 2022

JoF

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Malassezia spp. are commensals of the skin, oral/sinonasal cavity, lower respiratory and gastrointestinal tract. Eighteen species have been recovered from humans, other mammals and birds. They can also be isolated from diverse environments, suggesting an evolutionary trajectory of adaption from an ecological niche in plants and soil to the mucocutaneous ecosystem of warm-blooded vertebrates. In humans, dogs and cats, Malassezia-associated dermatological conditions share some commonalities. Otomycosis is common in companion animals but is rare in humans. Systemic infections, which are increasingly reported in humans, have yet to be recognized in animals. Malassezia species have also been identified as pathogenetic contributors to some chronic human diseases. While Malassezia species are host-adapted, some species are zoophilic and can cause fungemia, with outbreaks in neonatal intensive care wards associated with temporary colonization of healthcare worker’s hands from contact with their pets. Although standardization is lacking, susceptibility testing is usually performed using a modified broth microdilution method. Antifungal susceptibility can vary depending on Malassezia species, body location, infection type, disease duration, presence of co-morbidities and immunosuppression. Antifungal resistance mechanisms include biofilm formation, mutations or overexpression of ERG11, overexpression of efflux pumps and gene rearrangements or overexpression in chromosome 4.

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“…Cytology is a common method used for identifying Malassezia species. [9][10][11] All cytological samples were evaluated by the same person.…”

Section: Sampling Cytological Evaluation and Data Collectionmentioning

confidence: 99%

Prevalence of external ear disorders in Belgian stray cats

Bollez

Rooster

Furcas

et al. 2017

Journal of Feline Medicine and Surgery

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Objectives Feline otitis externa is a multifactorial dermatological disorder about which very little is known. The objective of this study was to map the prevalence of external ear canal disorders and the pathogens causing otitis externa in stray cats roaming around the region of Ghent, Belgium. Methods One hundred and thirty stray cats were randomly selected during a local trap-neuter-return programme. All cats were European Shorthairs. This study included clinical, otoscopic and cytological evaluation of both external ears of each cat. Prospective data used as parameters in this study included the sex, age and body condition score of each cat, as well as the presence of nasal and/or ocular discharge, and the results of feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV) Snap tests. Results Remarkably, very few (sub)clinical problems of the external ear canal were found in the stray cat population. Malassezia species was by far the most common organism found in the external ear canals of the 130 stray cats. A total of 96/130 (74%) cats were found to have Malassezia species organisms present in one or both ears based on the cytological examination. No correlation was found between the parameters of sex, age, body condition score, the presence of nasal and/or ocular discharge and FIV and FeLV status, and the presence of parasites, bacteria or yeasts. Conclusions and relevance This study provides more information about the normal state of the external ear canal of stray cats. The ears of most stray cats are relatively healthy. The presence of Malassezia species organisms in the external ear canal is not rare among stray cats.

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Malassezia pachydermatis keratomycosis in a dog

Cited by 10 publications

References 18 publications

Identification and antimicrobial susceptibility of microorganisms isolated from severe corneal ulcers of dogs in Thailand

Identification and antimicrobial susceptibility of microorganisms isolated from severe corneal ulcers of dogs in Thailand

Malassezia: Zoonotic Implications, Parallels and Differences in Colonization and Disease in Humans and Animals

Prevalence of external ear disorders in Belgian stray cats

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