Malaria Related Deaths among Children with Manifestations of Fever Symptoms on Admission in a Secondary Health Care Institution in Western Region of Ghana - a Retrospective Study

Orish, Verner N.; Sanyaolu, Adekunle; Mahama, Francois; Silverius, Bruku K.; Onyeabor, Onyekachi S.; Okorie, Chuku; Iriemenam, Nnaemeka C.

doi:10.9734/ijtdh/2018/42278

Cited by 2 publications

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“…2,29 Our finding is similar to the report of Umma et al 30 who reported malaria prevalence of 72.2% among febrile children attending Aminu Kano Teaching Hospital in Kano, Northwestern Nigeria. However, the malaria prevalence in this study is higher than previous reports from other parts of Nigeria like Ibadan, 31 Borno, 32 Lagos, 33 Anambra, 34,35 Enugun, 36 Ogun, 37 Jos, 38,39 Sokoto 40 and other malaria-endemic countries such as Cameroon, 41,42 Ethiopia, 43,44 Ghana, 45 Malawi 46 and Rwanda. 47 On the other hand, a higher malaria prevalence of 80.5% and 78% were reported among children in Ogun, southwestern Nigeria and Al Sabah, South Sudan, 48,49 respectively.…”

Section: Discussioncontrasting

confidence: 80%

Prevalence, Parasite Density and Determinants of Falciparum Malaria Among Febrile Children in Some Peri-Urban Communities in Southwestern Nigeria: A Cross-Sectional Study

Awosolu¹,

Yahaya²,

Termizi³

2021

IDR

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Background Malaria remains a serious public health problem worldwide, particularly in tropical and subtropical regions, including Nigeria. This study investigates the prevalence, parasite density and determinants of malaria among symptomatic children in some peri-urban communities in southwestern Nigeria. Methods This was a randomized cross-sectional and hospital-based study. The standard method of microscopy was employed. Thick and thin films were prepared and viewed under a light microscope to identify and quantify malaria parasites. A well-structured and pre-tested questionnaire was used to obtain the subject’s information on the demographic, socio-economic and environmental variables. Results A total of 380 (71.7%) participants were infected with Plasmodium falciparum with a mean parasite density of 1857.11 parasite/µL of blood. Malaria prevalence and mean parasite density were significantly higher among male compared to their female counterparts [80.3% vs 61.4% and 2026.46 vs 1619.63 parasite/µL of blood]. Similarly, age group ≤5 years had the highest malaria prevalence (92.2%) and mean parasite density (2031.66 parasite/µL of blood) than other age groups (AOR 2.281, 95% CI: 1.187–4.384, P < 0.05). The multivariate logistic analysis showed that malaria disease is significantly associated with having mother with no formal education (AOR 12.235, 95% CI: 3.253–46.021, P < 0.05), having well and river as a major source of household water supply (AOR 13.810, 95% CI: 3.012–63.314, P < 0.05 vs AOR 5.639, 95% CI: 1.455–21.853, P < 0.05) and presence of stagnant water around home (AOR 5.22, 95% CI: 2.921–9.332, P < 0.05). Furthermore, protective factors observed include ownership of mosquito bed net (AOR 0.474, 95% CI: 0.223–1.008, P < 0.05) and distance of home to hospital (AOR 0.279, 95% CI: 0.158–0.493, P < 0.05). Conclusion Malaria remains a serious public health problem in the study area. Adopting integrated malaria control measures including educating parents on malaria prevention and control strategies, distributing mosquito bed nets, and establishing larvae source management program is highly imperative.

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Section: Discussioncontrasting

confidence: 80%

Prevalence, Parasite Density and Determinants of Falciparum Malaria Among Febrile Children in Some Peri-Urban Communities in Southwestern Nigeria: A Cross-Sectional Study

Awosolu¹,

Yahaya²,

Termizi³

2021

IDR

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“…Here are some preventive actions you may take to keep malaria at bay and prevent it from spreading faster [43,44]. Use insect repellent on any exposed skin [45,46]. The repellent advised comprises 20-35% N,N-Diethyl-meta-toluamide (DEET).…”

Section: Preventionmentioning

confidence: 99%

A Systematic Review on Malaria Disease and Its Treatments Focus on Artemether Drug

PHALAK,

BODKE,

BODKE

et al. 2024

Int J Curr Pharm Sci

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Malaria is one of the infectious illnesses of the highest scientific significance and importance to international health organizations. Plasmodium falciparum, the parasite responsible for a highly severe form of the disease in Africa, has traditionally received the most attention. However, in the last two decades, the Plasmodium vivax parasite, which is linked to a large number of cases in Latin America, the Middle East, South and Southeast Asia, the Horn of Africa, and Oceania, has sparked enormous interest, owing to published evidence that it can cause severe malaria, among other things. Malaria is a worldwide public health problem, with a saw 247 million cases recorded in 2021. African countries accounted for approximately 94% of all reported cases. So far, over 200 distinct varieties of protozoa have been discovered and identified, with at least 13 of them being pathogenic to humans. The malaria parasite's life cycle is a complex process involving a mosquito with the species Anopheles and a vertebrate host. Artemether is a lipid-soluble artemisinin derivative. It is available in both oral and intramuscular forms. It is also available as a fixed-dose formulation with lumefantrine. Artemether-lumefantrine is one of the ACTs authorized by the WHO and is being used by the majority of countries transitioning from less effective medications to ACTs. However, the emergence of antimalarial medication resistance poses a significant challenge to malaria control. It works by killing the pathogenic organisms responsible for malaria. It is known as an antimalarial medication, and it is more effective than quinine therapies.

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Malaria Related Deaths among Children with Manifestations of Fever Symptoms on Admission in a Secondary Health Care Institution in Western Region of Ghana - a Retrospective Study

Cited by 2 publications

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Prevalence, Parasite Density and Determinants of Falciparum Malaria Among Febrile Children in Some Peri-Urban Communities in Southwestern Nigeria: A Cross-Sectional Study

Prevalence, Parasite Density and Determinants of Falciparum Malaria Among Febrile Children in Some Peri-Urban Communities in Southwestern Nigeria: A Cross-Sectional Study

A Systematic Review on Malaria Disease and Its Treatments Focus on Artemether Drug

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