Background: Ectopic pregnancy is still a global problem for women of reproductive age with increasing burden of the disease and increasing mortality especially for women living developing world like Africa. In Ghana studies evaluating the burden of ectopic pregnancy have been conducted in major centres like Korle-Bu and KATH but few in other centres. This study tends to evaluate the prevalence, clinical presentation and finding of ectopic pregnancy in a referral hospital in the Volta region of Ghana. Methodology: This was a 3 years (2013)(2014)(2015)(2016) retrospective review of all gynaecological admission in the Volta regional hospital. All ectopic pregnancy cases/ record were identified, retrieved and information on the socio-demographics, clinical presentations, intraoperative findings and outcome of surgery were all extracted for analysis. Result: A prevalence of 2.05% (53/2582) was recorded over the study period. 58.5% (31/53) of the women were married and between the age group of 21 -30. 47.2% (25/53) had primary school education. Lower abdominal pain was common in 98.1% (52//53), 69.2% (37/53) had vaginal bleeding while 96.4% (51/53). Fallopian tube pregnancy was seen in 96.2% (51/53) while 3.8% (2/53) were abdominal pregnancy. Tubal rupture and heamoperitoneum were seen in 73.6% (39/53) of the women. 78.4% (40/51) of the fallopian tube pregnancy occurred at the ampulla. All the women in this study were successfully managed with radical surgery. Conclusion: There is still the need to evaluate the prevalence of ectopic pregnancy in the region. Proper education of women of reproductive age and provision of equipment and skills to enable early diagnosis of ectopic pregnancy is very necessary in ensuring less radical and traumatic management with less implication on fertility of women post-surgery.
Introduction Malaria interventions including use of Sulfadoxine-Pyrimethamine as Intermittent Preventive Treatment (IPTp-SP) and distribution of Insecticide Treated Nets (ITNs) have been implemented through ante-natal clinic (ANC) services in Ghana. Yet, the high ANC attendance is not commensurate with the uptake of these interventions, with missed opportunities to deliver the interventions. This study sought to assess the health system factors affecting access and delivery of IPTp-SP and ITN as defined by the Ghana Malaria Policy Guideline to eligible pregnant women attending ANC clinic sessions. Methods A quantitative cross-sectional study was conducted in the Volta Region of Ghana, with data collected across three levels of health care delivery facilities, including hospitals, health centres and Community-Based Health Planning Service (CHPS) compounds. Data collection included structured observation checklists to document the communication and interaction between the ANC health staff and pregnant women. Additionally, structured questionnaires were used to elicit information on cadre, trainings attended, knowledge and delivery practices of health workers on IPTp-SP and ITN. Stata 16 was used for data analysis, and a defined delivery algorithm was used to compute appropriate and inappropriate delivery practices, using the Ghana policy directive as a guide. Predictors of appropriate delivery were determined using logistic regression analysis. Results Approximately 97% of the 680 ANC observations had complete information for analysis. Of these, 78% (511/657) were eligible for IPTp-SP after excluding women who have less than 16 weeks of gestation, G6PD deficient, malaria positive and have taken 5 doses of IPTp-SP prior to day of observation. Appropriate delivery of IPTp-SP was 76% (390/511). Despite the availability of SP, 15% (75/511) of all eligible women were not offered the medication and 37% (44/119) of inappropriate delivery was recorded during periods of stock out. ITNs were appropriately delivered to 59% (139) out of 237 eligible women. Thirty-two percent (77/237) of eligible women, mostly continuing ANC clients, were not given ITN despite stock availability. Conclusions IPTp-SP was appropriately delivered to most of the eligible pregnant women compared to ITN. While stock out of both intervention could account for inappropriate delivery, despite stock availability, IPTp-SP and ITN were not delivered to some eligible women.
Introduction Over the past two decades, there have been several global interventions including the Sustainable Development Goals (SDGs), aimed at improving health outcomes. Despite efforts by countries to achieve the SDG targets, mental health challenges remain major public health concerns globally. We examined the prevalence and predictors of depression, anxiety, and stress as well as the comorbidities of these mental health issues among adults. Materials and methods This was a community-based cross-sectional study conducted among 2456 adults in four districts of the Volta Region of Ghana using data from the UHAS-Yonsei University Partnership Project. We analysed the data using frequency, percentage, mean, standard deviation, correlation, and binary logistic regression. Results Overall, 51.8% of the participants had at least one of the mental health issues examined. The prevalence of a mental health issue was 25.2%, 53.3%, and 9.7% for depression, anxiety, and stress respectively. Participants constituting 8.3% experienced all three mental health issues as comorbidities. Participants’ level of formal education and income significantly predicted depression, anxiety, and stress respectively at the multivariable level. Adults with a tertiary level of education were, for instance, 68% (AOR = 0.32, 95%CI = 0.15–0.66), 65% (AOR = 0.35, 95%CI = 0.17–0.73), and 50% (AOR = 0.50, 95%CI = 0.33–0.76) less likely to experience depression, anxiety, and stress, respectively compared with those who had no formal education. Conclusion The majority of our study participants either experienced depression, anxiety, or stress. There were quite high comorbidities of the mental health issues among the adult population. To accelerate progress towards the achievement of SDG 3.4 target of promoting mental health and wellbeing for all by the year 2030, there is a need for effective implementation of the country’s 2012 Mental Health Act which makes provisions for the establishment of a Mental Health Fund. This could improve the financial circumstances of indigenes as income has been realised in the present study as an important factor influencing depression, anxiety, and stress among the adult population.
Malaria-endemic areas of the world are noted for high morbidity and mortality from malaria. Also noted in these areas is the majority of persons in the population having acquired malaria immunity. Though this acquired malaria immunity does not prevent infection, it resists the multiplication of Plasmodium parasites, restricting disease to merely uncomplicated cases or asymptomatic infections. Does this acquired malaria immunity in endemic areas protect against other diseases, especially outbreak diseases like COVID-19? Does malaria activation of innate immunity resulting in trained or tolerance immunity contribute to protection against COVID-19? In an attempt to answer these questions, this review highlights the components of malaria and viral immunity and explores possible links with immunity against COVID-19. With malaria-endemic areas of the world having a fair share of cases of COVID-19, it is important to direct research in this area to evaluate and harness any benefits of acquired malaria immunity to help mitigate the effects of COVID-19 and any possible future outbreaks.
The objective of this study was to evaluate cases of brought in dead (BID) patients in the accident and emergency unit of Effia-Nkwanta Regional Hospital through a retrospective study of a period of 3 years. A retrospective descriptive study of BID cases from the death register and patients' records of the accident and emergency unit of the hospital was carried out from January 2011 to December 2013. 31% (180/574) of BID cases were recorded over the study period with the age range from below 1 year to over 70 years. They were 58.5% male and 41.5% female with a ratio of 1.4:1. The majority of the BID cases (20.7%) were patients above 70 years and most cases (40.8%) have no known clinical condition associated with the death. The majority of the unexplained deaths were highest among young adults between the ages 30 and 40 years (22.6%). The highest cases of BID (20%) were seen in the month of December and majority of the cases (72.5%) lived within the metropolis. This study showed a concerning trend of BID cases in the hospital with a high prevalence among the elderly and unexplained death among the young adults. Hence there is an urgent need to upgrade hospitals in the area with the hope of relieving the burden off Effia-Nkwanta Regional Hospital and also a need to increase health promotion strategies among the people of the area so as to instill health seeking behavior in order to prevent avoidable deaths.
Infectious disease is a serious global health problem. However, its negative impact is felt more in sub Saharan Africa. Epidemiological figures have shown that the burden of infectious disease is highest in the African continent especially in sub Saharan Africa. A majority of people leaving in sub Saharan Africa are poor and their exposure to infectious disease worsens their poverty situation. Aside impoverishing infected individuals, infectious diseases also directly negatively impact the economy of the country involved, reducing economic growth and productivity. Diseases like malaria, HIV, tuberculosis TB, and other epidemic prone diseases like Cholera and Ebola constantly pose a threat to economic development in Sub Saharan Africa. It is therefore pertinent to invest in disease prevention strategies to curb the burden and reduce the impact of infectious diseases on the economy of countries in sub Saharan Africa. This mini review re-echoes the burden of infectious diseases and discusses ways and strategies to reduce the burden of these diseases and the economic benefits that will be accrued at the long run.
Asymptomatic Plasmodium falciparum infections are very common in older children and can pose a great problem for malaria control programs. This study was a cross sectional study-design that looked at the prevalence of Plasmodium falciparum infection among school aged children in five primary schools in 3 districts in the Volta Region of Ghana. Questionnaires were administered and blood samples were collected for malaria detection using RDT and microscopy. Pearson chi square test was used to evaluate the association between P. falciparum infection and other variables in the study. A total of 550 primary school children were enrolled in this study. Three hundred and five children (55.45%) were positive for malaria with RDT and 249(45.27%) were malaria positive with microscopy. Children from Evangelical Presbyterian (EP) primary school in Afegame and Davanu primary schools, both in remote, rural and farming communities had the highest prevalence of P falciparum (RDT,
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