2010
DOI: 10.1590/s0104-12902010000100006 View full text |Buy / Rent full text
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Abstract: ResumoDurante a evolução do gênero Homo a infecção por malária exerceu papel biológico chave, influenciando até o desenvolvimento antropológico. Os Plasmódios causadores da malária desenvolveram dois tipos de evolução, segundo um ponto de vista biológico, e filogenético. Em particular, os Plasmó-dios vivax, malariae, e ovale poderiam ter coevoluído com a espécie humana ou ter atingido esta durante as fases mais antigas da evolução do gênero HOMO. SummaryDuring the evolution of the genus Homo, with regard to s… Show more

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“…Further investigation of the relationship between malaria parasites and chimpanzees in natural conditions is important to understand the significance of malaria infection for wild great ape populations' health, and it can serve as a model to understand the host-parasite relationship in human populations, where malaria is believed to have acted as an important driver of recent evolution (Carter and Mendis, 2002;Sabbatani et al, 2010). Wild habituated AGA communities are ideal targets to pursue investigations on illness related to malaria infection.…”
Section: Pathogenicity Of Malaria Parasites In African Great Apesmentioning
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rupbmjkragerfmgwileyiopcupepmcmbcthiemesagefrontiersapsiucrarxivemeralduhksmucshluniversity-of-gavle
“…Further investigation of the relationship between malaria parasites and chimpanzees in natural conditions is important to understand the significance of malaria infection for wild great ape populations' health, and it can serve as a model to understand the host-parasite relationship in human populations, where malaria is believed to have acted as an important driver of recent evolution (Carter and Mendis, 2002;Sabbatani et al, 2010). Wild habituated AGA communities are ideal targets to pursue investigations on illness related to malaria infection.…”
Section: Pathogenicity Of Malaria Parasites In African Great Apesmentioning
“…1,7-17 g-CAs were recently discovered by our groups analyzing the amino acid sequences of CAs from Plasmodia, a large genus of parasitic protozoa responsible of malaria in humans and other animals. 1,[18][19][20][21][22][23] In the present Letter we reanalyzed the findings which led us to introduce this new CA class, suggesting a different sequence alignment with the CAs of other classes and proposing a homology model for understanding the structural features of this new family. Our findings show that, although g-CAs retain many structural features of the a-class, they present a distinctive zinc coordination mode, making their catalytic site unique and different from that found in the other CAs and thus justifying their classification in a new class.…”
Section: G-class A-classmentioning
“…Plasmodia that can infect humans are represented by five species: Plasmodium falciparum, P. vivax, P. ovale, P. malariae and P. knowlesi [1][2][3][4][5][6][7]. Plasmodia have the ability to move from intestinal cells towards liver cells through the portal circulation.…”
Section: Introductionmentioning