Malaria: Host-Pathogen Biology

Iron deficiency protects inbred mice against infection with Plasmodium chabaudi

“…and that protection from malaria observed in individuals with the minor thalassemias or with iron deficiency is related to the lowering of mean corpuscular hemoglobin. Wyler (13) proposed that activity of erythrocyte catalase, needed to scavenge H202 produced intracellularly…”

Comparison of Serum Concentrations of Total Cholesterol and Total Lipid in Different Groups of Female Tuberculosis Patients

“…Cholesterol rich diet could therefore be incorporated in the treatment/management of tuberculosis patients. The observation of higher mean serum cholesterol level in the patients above 60 years of age could be attributed to the general rise of cholesterol level associated with ageing, or genetic factors (Wyler, 1982) or dietary factor (Eluwa et al, 1987).…”

The schizontocidal activity of Spathodea campanulata leaf extract on Plasmodium berghei berghei in mice

“…Malaria, one of the most important diseases affecting the population over wide areas of the world (Wyler, 1982), is estimated to be responsible for the deaths of one million infants and young children each year in Africa alone (WHO, 1985). The eradication of the disease has been hampered by the emergence and spread of multidrugresistant malarial parasites, especially Plasmodium falciparum strains resistant to many antimalarial drugs (WHO, 1985;Peters, 1984).…”