Malakoplakia of the Skin: Report of a Case

Malakoplakia

“…CUTANEOUS MALAKOPLAKIA Examples of cutaneous malakoplakia have been reported by the following authors: Rao (1969), Leclerc and Bernier (1972), Scullin and Hardy (1972), Moore, Stokes and Canabas (1973), Price, Hanrahan and Florida (1973), Lou and Teplitz (1974), Arul and Emmerson (1977), Reiner et al, Colby (1978), Nieland et al (1979,1981), Sencer et al (1979), Chaudhry et al (1980) and Almagro et al (1981. These cases comprised six females and seven males.…”

Clinical Evaluation and Surgical Management of Ocular Malakoplakia of the Caruncle and Periorbital Region: A Report of Two Case and Literature Review

“…Intact bacterial and fungal fragments have been identified in malakoplakia lesions occurring in diverse anatomical locations. [7][8][9][10][11] Mc Clure proposed that continuous or recurrent bacterial infection, or infection by a large number of organisms, might lead to the fusion of phagosomes, forming giant cytosegrosomes that undergo calcification to create Michaelis-Gutmann bodies, based on the research by Lynch et al 12,13 The more typical diffuse pattern of malakoplakia could then occur if the ongoing inflammatory reaction extended beyond the tubular confines. It is important to note that the controversy surrounding recurrent infections and the presence of bacteria within the slides and sections is not necessarily conclusive.…”

Generalized eruptive histiocytoma: report of a case and electron microscopic finding of Michaelis-Gutmann bodies

“…The findings of MG bodies in the 1975 lesion was surprising, since MG bodies are characteristic of cutaneous malakoplakia (Moore et al, 1973;Price et al, 1973;Te Yong Lou& Teplitz, 1974;Arul &Bmmerson, 1977;Sencer era/., 1979;Almagro ef a/., 1981;Nieland era/., 1981). The present case does not represent cutaneous malakoplakia, since generalized skin lesions are present and MG bodies have not been observed in subsequent skin biopsies (Nieland et al, 1981).…”