“…Bile duct hamartomas (BH) (also known as von Meyenburg complexes) are benign lesions caused by failure of the small interlobular bile ducts to involute at the late phase of embryogenesis [ 12 – 14 ]. BHs are asymptomatic and disconnected bile duct lesions with only limited dilation, lined by biliary epithelium.…”
Section: Ductal Abnormalitiesmentioning
confidence: 99%
“…9 a), with comet-tail artefacts [ 4 , 13 ]. The pattern they produce has been described as a “snowstorm” [ 14 ]. They are poorly visible on CT, round or irregular in shape, with strict fluid attenuation and no enhancement (Fig.…”
Hepatic cysts (HC) are sac-like structures mainly filled with liquid and showing a distinct membrane. They are usually found incidentally through imaging. A wide spectrum of imaging patterns may be observed for common and uncommon, neoplastic and non-neoplastic diseases. While simple hepatic cysts occur frequently and do not require any treatment or follow-up, non-typical cysts should be carefully analysed to avoid misdiagnosing a lesion that would require appropriate management. Therefore, adequate knowledge of all the relevant imaging patterns is critical to secure an accurate diagnosis. The aim of this review is to describe the imaging features of the different types of hepatic cysts.
“…Bile duct hamartomas (BH) (also known as von Meyenburg complexes) are benign lesions caused by failure of the small interlobular bile ducts to involute at the late phase of embryogenesis [ 12 – 14 ]. BHs are asymptomatic and disconnected bile duct lesions with only limited dilation, lined by biliary epithelium.…”
Section: Ductal Abnormalitiesmentioning
confidence: 99%
“…9 a), with comet-tail artefacts [ 4 , 13 ]. The pattern they produce has been described as a “snowstorm” [ 14 ]. They are poorly visible on CT, round or irregular in shape, with strict fluid attenuation and no enhancement (Fig.…”
Hepatic cysts (HC) are sac-like structures mainly filled with liquid and showing a distinct membrane. They are usually found incidentally through imaging. A wide spectrum of imaging patterns may be observed for common and uncommon, neoplastic and non-neoplastic diseases. While simple hepatic cysts occur frequently and do not require any treatment or follow-up, non-typical cysts should be carefully analysed to avoid misdiagnosing a lesion that would require appropriate management. Therefore, adequate knowledge of all the relevant imaging patterns is critical to secure an accurate diagnosis. The aim of this review is to describe the imaging features of the different types of hepatic cysts.
“…Indeed, reliable biopsies are not the least important thing in oncological research (Rotenberg et al, 2004). Clinical data of a new manual biopsy system, the 'Spirotome', have been recently reported in human beings for breast (Rotenberg et al, 2004;Janssens et al, 2006;Cusumano et al, 2008) and liver (Nasr et al, 2006) biopsies.…”
Section: Discussionmentioning
confidence: 99%
“…However, the results are sometimes unsatisfactory (De Rycke et al, 1999;Cole et al, 2002). Recently, a new biopsy device called the 'Spirotome' (Medinvents, Hasselt, Belgium) has been developed and successfully used for biopsy of the breast, lymph node, peritoneum, bone, and liver in humans (Janssens et al, 2002;Rotenberg et al, 2004;Nasr et al, 2006;Cusumano et al, 2008). The Spirotome system has four main parts: cutting canula, trocar, helical tissue receiving needle, and releasing device.…”
Several methods for obtaining specimens from abdominal organs have been described. Imaging-guided biopsy, particularly ultrasound-guided biopsy, is the most frequently used in clinical trials. The aim of this study was to evaluate the diagnostic quality of histological samples obtained with a manual biopsy device (Spirotome) on biopsies of the liver, spleen, and kidney, in fresh canine organs and in live animals in a clinical trial. The study was divided into two different parts, one using normal fresh canine organs with a total of 60 biopsies, 20 of liver, spleen, and kidney, respectively; and one on clinical patients, including 35 biopsied lesions in 28 animals (25 dogs and three cats) for a total of 95 biopsies. All the biopsy samples were considered satisfactory from canine cadavers, and all specimens were diagnostic in clinical cases. The technique was accurate and safe and no major complications were noted.
“…This method provides reliable diagnostic samples and is less invasive than the surgical approach. 6 A manual biopsy device called Spirotomet (Medinvents, 3500 Hasselt, Belgium) has been developed and successfully used in human patients for collecting biopsies of the breast, lymph node, peritoneum, and liver 2,3,8,11,13 and in veterinary medicine for sampling liver, spleen, and kidney. 16 Vignoli and Saunders 16 found the Spirotome system to be safe and easy to use for abdominal ultrasound-guided biopsies in dogs and cats, providing high-quality biopsy samples of the liver, spleen, and kidneys.…”
The aim of this study was to evaluate a large-core manual biopsy device (Spirotome(®), Medinvents, 3500 Hasselt, Belgium) for liver sampling and histologic diagnosis in green iguanas (Iguana iguana). The study included eight green iguanas, and two ultrasound-guided biopsies were collected for each lizard, for 16 biopsies in total. The procedure was carried out under general anesthesia induced by intravenous injection of propofol (10 mg/kg) maintained with a mixture of 2.0% isoflurane and 0.8-1.2 L/min oxygen after tracheal intubation. Fourteen (87.5%) of the 16 biopsies were considered diagnostic. Liver biopsy quality was assessed according to sample size and tissue preservation. In particular, mean length (16.2 ± 4.5 mm), width (2.2 ± 0.5 mm), area (34.8 ± 6.9 mm(2)), and number of portal areas (9.4 ± 3.9) of each biopsy were recorded for all green iguanas. The total available surface of the sections obtained from the biopsies and their grade of preservation enabled a satisfactory evaluation of the parenchymal architecture. One of the green iguanas in the study died the day after the procedure due to severe hemocoeloma. Risk assessment evaluation suggested that small green iguanas may not be suitable for this biopsy procedure.
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