Malacoplakia of the Vallecula Masquerading as a Malignancy

Mannan, Abul Ala Syed Rifat; Sharma, Mehar Chand; Bahadur, Sudhir

doi:10.1177/014556131109000318

Cited by 6 publications

(3 citation statements)

References 18 publications

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“…Malakoplakias continue to be reported to occur at unusual sites, such as the spleen, nasal cavity, and oropharynx [ 16 – 18 ]. The exact frequency of the association of malakoplakia with malignancy is not known at present and whether all cases of malakoplakia are to be definitively managed with surgery due to this risk is open for deliberation.…”

Section: Discussionmentioning

confidence: 99%

Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the Literature

Guha

Liu

2015

Case Reports in Pathology

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Although malakoplakia has been reported to occur at various body sites, pancreatic malakoplakia with simultaneous colonic involvement is very rare. Lesions of malakoplakia can masquerade as tumor masses leading to unwanted resections. Nevertheless, malakoplakia can occur in association with frank carcinomas, especially in the colon. By reporting a case of pancreatic malakoplakia diagnosed by fine needle aspiration cytology, this paper aims to describe cytologic features of malakoplakia and to further review findings from previous reported cases of pancreatic malakoplakia in the literature. With advances in minimally invasive, image-guided aspiration technologies, cytomorphological analyses can diagnose lesions of malakoplakia. This may help avoid surgeries that would have otherwise been carried out due to a misleading impression of tumor. However challenges remain as to the further management of patients diagnosed with this condition. More studies are necessary to determine the probability of malignancies arising in association with malakoplakia, in order to devise appropriate treatment protocols.

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Section: Discussionmentioning

confidence: 99%

Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the Literature

Guha

Liu

2015

Case Reports in Pathology

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“…We have retrieved seven reports about the malakoplakia of the larynx. Among them, the malakoplakia of three cases occurred in the vallecula, [12][13][14] one case in the epiglottis, 15 three cases in the false vocal cord (including this case). 16,17 This case report is combined with a literature review (Table 1).…”

Section: Literature Reviewmentioning

confidence: 99%

Malakoplakia of Larynx: A Case Report and Literature Review of Localized Malakoplakia of Larynx

Zeng

Yang

et al. 2022

Journal of Voice

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“…Malakoplakia is a rare inflammatory disease process which often arises as soft, yellow or fleshcolored plaques or papules, typically within the genitourinary or gastrointestinal tracts [1]; however, this clinical presentation varies depending on the site of involvement [2]. Cutaneous lesions of malakoplakia present as ulcerated plaques or nodules [3,4] while visceral involvement more commonly forms masses and affects sites such as the abdomen or the head and neck [2,5]. Oral involvement is exceedingly rare [1,6,7].…”

Section: Introductionmentioning

confidence: 99%

Malakoplakia involving the maxilla: A case report and a review of the literature

Roark,

Bruett,

Dominger

et al. 2024

Preprint

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Malakoplakia is a rare inflammatory disorder which typically occurs in immunocompromised patients secondary to impaired bactericidal activity of macrophages. While this entity commonly arises in the genitourinary and gastrointestinal tracts, lesions of the head and neck have been reported only rarely, with oral cavity involvement reported in 3 cases. The most common presentation of head and neck malakoplakia is that of a cutaneous flesh-colored papule or nodule. This case report, however, illustrates the first time malakoplakia is identified affecting the maxilla and maxillary alveolar ridge mucosa. Histochemical and immunohistochemical stains are presented and include positivity for PAS, von Kossa stain, iron stain, and CD68 and negativity for GMS and Gram stains, indicating an inability to demonstrate microbial infection. Thus, clinicians and pathologists alike should be aware of malakoplakia as a pathologic entity when forming differential diagnoses, particularly in immunosuppressed individuals.

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Malacoplakia of the Vallecula Masquerading as a Malignancy

Cited by 6 publications

References 18 publications

Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the Literature

Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the Literature

Malakoplakia of Larynx: A Case Report and Literature Review of Localized Malakoplakia of Larynx

Malakoplakia involving the maxilla: A case report and a review of the literature

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