Magnetically separable graphene oxide anchored sulfonic acid: a novel, highly efficient and recyclable catalyst for one-pot synthesis of 3,6-di(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-5-carbonitriles in deep eutectic solvent under microwave irradiation

Abstract

A magnetic separable sulfonic acid catalyst was prepared and applied for the synthesis of 3,6-di(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-5-carbonitriles via three-component reaction of 1-phenyl-3-(pyridin-3-yl)-1H-pyrazol-5-amine, β-ketonitrile and aldehydes in DES.

Determination of sulfadimethoxine in milk with aptamer‐functionalized Fe3O4/graphene oxide as magnetic solid‐phase extraction adsorbent prior to HPLC

“…The diffraction pattern of Fe 3 O 4 /GO composite with the main peaks at 2 θ = 30.2, 35.2, 43.2, 53.4, 57.2, and 62.5° are indexed to (220), (311), (400), (422), (511), and (440) planes of the magnetite structure (JPPDS NO.19‐0629) [35]. However, no diffraction peak of GO was observed for Fe 3 O 4 /GO, indicating the destruction of the regular layer stacking of GO due to crystal growth of Fe 3 O 4 between interlayer of GO sheets [36, 37].…”

Magnetically Separable Transition Metal Ferrites: Versatile Heterogeneous Nano‐Catalysts for the Synthesis of Diverse Bioactive Heterocycles

“…Pyrazolo[3,4‐ b ]pyridines are found to possess diverse biological activities that include antioxidant, antimicrobial, antimicrobial, anticancer and many more efficacies. Zhang et al . efficiently synthesized and well characterized nano‐CoFe 2 O 4 doped graphene oxide anchored sulfonic acid (CoFe 2 O 4 ‐GO‐SO 3 H) by XRD, SEM, TEM, and VSM techniques.…”

Development of different deep eutectic solvent aqueous biphasic systems for the separation of proteins

“…[2][3][4][5][6] Additionally, DESs can be easily obtained by heating two or three components at a proper ratio, and the products need not be puried. Based on this, DESs have been regarded as excellent substitutes for toxic organic solvents in many elds such as catalysis, 7 organic synthesis, 8 and separation. [9][10][11] Proteins are bioactive macromolecules, which play an important role in life activities and have extensive applications in food and medical elds.…”