Magnetic solid phase extraction for determination of drugs in biological matrices

Vasconcelos, Ingrid; Fernandes, Christian

doi:10.1016/j.trac.2016.11.011

Cited by 182 publications

(65 citation statements)

References 98 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, SPE still has some drawbacks, such as the need for evaporation and reconstitution steps and the relatively high solvent consumption. Derived from SPE, MSPE was first proposed in 1999 [83][84][85], which has drawn considerable attention. MSPE based on a magnetic adsorbent was gradually developed for sulfonamide enrichment owing to its high efficiency for separation and pre-enrichment of target compounds from complex matrices [16,[19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36].…”

Section: Patternsmentioning

confidence: 99%

Trends in sensitive detection and rapid removal of sulfonamides: A review

Xie

Huang

Zheng

et al. 2020

J of Separation Science

View full text Add to dashboard Cite

Sulfonamides in environmental water, food, and feed are a major concern for both aquatic ecosystems and public health, because they may lead to the health risk of drug resistance. Thus, numerous sensitive detection and rapid removal methodologies have been established. This review summarizes the sample preparation techniques and instrumental methods used for sensitive detection of sulfonamides.Additionally, adsorption and photocatalysis for the rapid removal of sulfonamides are also discussed. This review provides a comprehensive perspective on future sulfonamide analyses that have good performance, and on the basic methods for the rapid removal of sulfonamides. K E Y W O R D Srapid removal, sample preparation techniques, sensitive detection, sulfonamides 1634

show abstract

Section: Patternsmentioning

confidence: 99%

Trends in sensitive detection and rapid removal of sulfonamides: A review

Xie

Huang

Zheng

et al. 2020

J of Separation Science

View full text Add to dashboard Cite

show abstract

“…The magnetic materials comprise of a magnetic metal oxide nanoparticle core, usually Fe 3 O 4 , coated with inorganic or organic materials, such as silica, alumina, chitosan, or polypyrrole, while the coating can be modified with functional groups for improved sorption capability. A MSPE application is similar to DSPE, with the difference that the sorbent can be collected by means of a magnet (Figure 2b) [19]. While solid-phase techniques can be used for aqueous samples or sample solutions, matrix solid-phase dispersion (MSPD) can be applied directly for the extraction of analytes from solid, semi-solid, and viscous samples.…”

Section: Spementioning

confidence: 99%

Food Sample Preparation for the Determination of Sulfonamides by High-Performance Liquid Chromatography: State-of-the-Art

et al. 2018

View full text Add to dashboard Cite

Antibiotics are a common practice in veterinary medicine, mainly for therapeutic purposes. Sectors of application include livestock farming, aquacultures, and bee-keeping, where bacterial infections are frequent and can be economically damaging. However, antibiotics are usually administered in sub-therapeutic doses as prophylactic and growth promoting agents. Due to their excessive use, antibiotic residues can be present in foods of animal origin, which include meat, fish, milk, eggs, and honey, posing health risks to consumers. For this reason, authorities have set maximum residue limits (MRLs) of certain antibiotics in food matrices, while analytical methods for their determination have been developed. This work focuses on antibiotic extraction and determination, part of which was presented at the "1st Conference in Chemistry for Graduate, Postgraduate Students and PhD Candidates at the Aristotle University of Thessaloniki". Taking a step further, this paper is a review of the most recent sample preparation protocols applied for the extraction of sulfonamide antibiotics from food samples and their determination with high-performance liquid chromatography (HPLC), covering a five-year period.

show abstract

“…In MSPE process, extraction time is also an important parameter for effective extraction of analytes because MSPE is not an exhaustive extraction but a partition equilibrium process of the analytes between adsorbents and sample solution. In this work, the effect of different extraction time (2,5,10,15,20, and 30 min) on extraction recovery was investigated, respectively. Figure 2D shows that the extraction recoveries of CKs increased with the increase in extraction time from 2 to 20 min, and then decreased slightly after 20 min, which suggested that 20 min was optimal for extraction.…”

Section: Effect Of Extraction Timementioning

confidence: 99%

Graphene oxide composites for magnetic solid‐phase extraction of trace cytokinins in plant samples followed by liquid chromatography–tandem mass spectrometry

Cheng

Qin

et al. 2018

J of Separation Science

View full text Add to dashboard Cite

In this work, an easy, effective, and sensitive method based on graphene oxide@silica@magnetite composites as adsorbent of magnetic solid-phase extraction combined with liquid chromatography and tandem mass spectrometry, was established and validated for the trace analysis of cytokinins in different plants. The prepared magnetic composite was characterized by infrared spectroscopy, transmission electron microscopy, Brunauer-Emmett-Teller analysis, and magnetic hysteresis. Under the optimized conditions, good linearities in the range of 0.5-100 ng/mL were obtained with the corresponding linear correlation coefficient >0.9989 for the investigated four cytokinins, and good sensitivity levels were achieved with low detection limits ranging from 93 to 120 pg/mL. The established magnetic solid-phase extraction with liquid chromatography and tandem mass spectrometry method has been validated in the separation and analysis of four cytokinins in plant samples with good recoveries between 78.9 and 97.3% for four cytokinins with the relative standard deviations lower than 13.5%.

show abstract

Magnetic solid phase extraction for determination of drugs in biological matrices

Cited by 182 publications

References 98 publications

Trends in sensitive detection and rapid removal of sulfonamides: A review

Trends in sensitive detection and rapid removal of sulfonamides: A review

Food Sample Preparation for the Determination of Sulfonamides by High-Performance Liquid Chromatography: State-of-the-Art

Graphene oxide composites for magnetic solid‐phase extraction of trace cytokinins in plant samples followed by liquid chromatography–tandem mass spectrometry

Contact Info

Product

Resources

About