Magnetic resonance neurography in the diagnosis of a retroperitoneal ganglioneuroma: Case report and literature review

Abstract

Magnetic resonance neurography is a technique for identifying anatomy and pathologic lesions of nerves, and has emerged as a helpful technique for localizing lesions and elucidating the underlying etiology. Ganglioneuromas are highly differentiated benign tumors. This lesion is rare and exhibits undetermined symptoms, the features of using the magnetic resonance neurography are a great ally to determine its diagnosis. The authors illustrate a case of retroperitoneal ganglioneuroma emphasizing its image characteristics using magnetic resonance neurography with the diagnosis confirmed by histopathological examination.

A huge retroperitoneal ganglioneuroma in a middle‑aged patient: Report of a diagnostically challenging case with review of the literature

“…Symptoms, when present, are relatively non-specific and include abdominal, back and neck pain, vomiting, hemoptysis and shortness of breath due to the pressure exerted on adjacent orangs by the enlarging tumor. Referred pain to the lower limbs with paresthesia and numbness to due to big retroperitoneal ganglioneuroma has also been documented (2,(14)(15)(16). The patient of the present study had abdominal and back pain.…”

“…Ganglioneuromas (GNs) are highly differentiated benign tumors that arise from neural crest cells and may develop anywhere along the sympathetic chain (1). They are most commonly present in the posterior mediastinum (41.5%) and the retroperitoneum (37.5%) (2). The tumors are usually detected incidentally during radiological imaging for unrelated conditions.…”

Large retroperitoneal ganglioneuroma revealed by a left ovarian endometrioma: A case report

“…Imaging methods are crucial for surgical planning, providing insights into the tumor’s size, origin organ, local expansion, and conjunction with surrounding organs and arteries. 2 , 4 , 6 However, it is imperative to note that the misinterpretation of a benign neuroblastic tumor as a sarcoma by a CT scan has been documented, underscoring the inadequacy of imaging features in providing an accurate diagnosis for this condition.…”

“… 3 They are typically asymptomatic, whereas the majority of cases lack definitive clinical manifestations, with incidental discovery occurring through radiological imaging while investigating unrelated pathologies. 4 Symptomatic presentation ensues as a consequence of the tumor’s progressive growth and compression of neighboring organs and vasculature. 2 A conclusive diagnosis relies on histopathological examination, which typically reveals a blend of ganglion cells and Schwann cells without immature elements.…”

“…2 A conclusive diagnosis relies on histopathological examination, which typically reveals a blend of ganglion cells and Schwann cells without immature elements. 2 , 4 Surgical intervention remains the sole curative option, with the efficacy contingent upon the size and regional expansion of the tumor. 2 , 3 …”