Magnetic resonance imaging of intramedullary spinal cord schwannomas

Colosimo, Cesare; Cerase, Alfonso; Denaro, Luca; Maira, Giulio; Greco, Romano

doi:10.3171/spi.2003.99.1.0114

Cited by 39 publications

(53 citation statements)

References 18 publications

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“…Generally, schwannomas display the classic pattern of variability in cellularity between densely cellular Antoni A and loosely cellular Antoni B regions. Schwannomas are usually devoid of axons in the tumor cells [2,9,12]. These features support the diagnosis of present spinal cord lesions as traumatic neuromas rather than schwannomas.…”

supporting

confidence: 57%

A Case Report of Traumatic Neuroma of the Cervical Spinal Cord in a Dog

Park

Kojima

Hatai

et al. 2012

The Journal of Veterinary Medical Science

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ABSTRACT. Traumatic neuroma of the cervical spinal cord was diagnosed in a 14-year-old male mixed-breed dog. A gross view showed two intradural extramedullary masses, measuring 1 and 0.6 cm in length and 0.7 and 0.4 cm in diameter, attached to the left side of the spinal cord at the level of the sixth and seventh cervical vertebrae. Microscopically, the cervical spinal masses comprised interlacing fascicles of axons and Schwann cells surrounded by collagenous stroma. Immunohistochemically, the fascicles were stained positively for neurofilament and S-100 proteins. Ultrastructurally, variably sized myelinated fibers and onion bulb-like structures were observed. To our knowledge, this is the first report of a traumatic neuroma in the cervical spinal cord of a dog.

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supporting

confidence: 57%

A Case Report of Traumatic Neuroma of the Cervical Spinal Cord in a Dog

Park

Kojima

Hatai

et al. 2012

The Journal of Veterinary Medical Science

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“…3,6) Evidence of von Recklinghausen's disease is present about 12% of reported cases. 2,5) In our study, intramedullary spinal schwannoma was more common in middle-aged men with prolonged chronic cord compression. The most common site was the cervical cord followed by the thoracic cord.…”

Section: Discussionmentioning

confidence: 78%

“…Intramedullary spinal schwannoma can appear as a well demarcated, highly enhanced, regularly shaped mass. 3,5,7,10) In the present study, variations in preoperative MR imaging features presented many difficulties for differential diagnosis. Thus, definitive preoperative diagnosis of intramedullary schwannoma is difficult based only on MR imaging, unless a predominantly extramedullary component or possibly nerve root thickening is visible.…”

Section: Discussionmentioning

confidence: 99%

Preoperative Diagnosis of Intramedullary Spinal Schwannomas

Yao

Chen

et al. 2011

Neurol. Med. Chir.(Tokyo)

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Intramedullary spinal schwannomas are rare benign spinal cord tumors and are easily misdiagnosed because of the imaging characteristics shared with intramedullary glioma. Correct preoperative definitive diagnosis is essential for treatment and prognosis. To improve the preoperative diagnostic strategy, clinical and imaging data of seven patients with intramedullary spinal schwannoma (6 men, mean age 44 years, mean duration of illness 4.2 years) treated in our department between 2003 and 2010 were collected and retrospectively evaluated. The cervical cord was affected in five patients, followed by the thoracic cord in two. All seven cases were misdiagnosed as intramedullary glioma based on the imaging characteristics. Comparison of the clinical features of these 7 patients with those of patients with intramedullary tumors (173 ependymomas and 70 astrocytomas) admitted during the same period revealed significant differences in somatic pain and root pain as the initial symptoms between intramedullary spinal schwannomas and ependymomas (p ＝ 0.005) and between intramedullary spinal schwannomas and astrocytomas (p ＝ 0.019), but not between ependymomas and astrocytomas (p ＝ 0.175). Root or somatic pain as an initial symptom is important for the preoperative diagnosis of intramedullary spinal schwannoma, especially if the imaging characteristics are not entirely specific.

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“…Schwannoma in its classic form consists of spindle-shaped cells with pale, eosinophilic cytoplasm arranged in two characteristic patterns: Antoni A (compact, hypercellular, well-organized spindle cells in a palisading pattern) and Antoni B (hypocellular, loose-textured pleomorphic cells with predominantly myxoid cytoplasm). In addition, schwannomas show diffuse immunoreactivity for S-100 protein[6]–[8],[11].…”

Section: Discussionmentioning

confidence: 99%

Schwannoma of the conus medullaris: a rare case

Canbay¹,

Hastürk²,

Markoç³

et al. 2011

Chin J Cancer

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Intradural schwannoma of the conus medullaris is a rare form of spinal neoplasm, which commonly occurs in the lumbar region. Conus medullaris level is unusual for schwannomas. A 49-year-old woman presented with chronic sciatica, mild bladder dysfunction, and paresthesia in the buttocks. Magnetic resonance imaging of the spine showed a mass lesion in the conus medullaris region with nerve compression. The tumor was completely resected and diagnosed histologically as schwannoma. The patient recovered after surgery. Clinical and radiologic features of this rare tumor are reviewed and are accompanied by literature findings.

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Magnetic resonance imaging of intramedullary spinal cord schwannomas

Cited by 39 publications

References 18 publications

A Case Report of Traumatic Neuroma of the Cervical Spinal Cord in a Dog

A Case Report of Traumatic Neuroma of the Cervical Spinal Cord in a Dog

Preoperative Diagnosis of Intramedullary Spinal Schwannomas

Schwannoma of the conus medullaris: a rare case

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