Magnetic resonance imaging analysis of the upper cervical spine extensor musculature in an asymptomatic cohort: an index of fat within muscle

Elliott, James M.; Galloway, Graham J.; Jull, Gwendolen; Noteboom, J. Timothy; Centeno, Christopher J.; Gibbon, Wayne

doi:10.1016/j.crad.2004.08.013

Cited by 55 publications

(62 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This procedure, which has shown high reliability, has been used in previous studies. 19,20,24,25 Nevertheless, to ensure a good degree of reliability, two experienced radiologists identified and measured CSA in both muscles separately. The interexaminer agreement was tested for each muscle on each side by means of the repeated-measures analysis of variance (ANOVA) intraclass correlation coefficient.…”

Section: Mri Proceduresmentioning

confidence: 99%

Association of Cross-Sectional Area of the Rectus Capitis Posterior Minor Muscle with Active Trigger Points in Chronic Tension-Type Headache

Fernández‐de‐las‐Peñas

Cuadrado²,

Arendt‐Nielsen³

et al. 2008

American Journal of Physical Medicine &Amp; Rehabilitation

View full text Add to dashboard Cite

show abstract

Section: Mri Proceduresmentioning

confidence: 99%

Association of Cross-Sectional Area of the Rectus Capitis Posterior Minor Muscle with Active Trigger Points in Chronic Tension-Type Headache

Fernández‐de‐las‐Peñas

Cuadrado²,

Arendt‐Nielsen³

et al. 2008

American Journal of Physical Medicine &Amp; Rehabilitation

View full text Add to dashboard Cite

show abstract

“…The gastrocnemius/soleus muscle fat content was estimated 14 days before and after 29 and 56 days of bed rest from axial T1-spin echo-weighted images obtained from the superior aspect of the calcaneus to the proximal tibia of both legs (Philips Intera 1.5 T magnetic resonance imaging), as previously described (22). We used a relaxation time of 425 ms and an excitation time of 16 ms based on one excitation.…”

Section: Methodsmentioning

confidence: 99%

Physical Inactivity Differentially Alters Dietary Oleate and Palmitate Trafficking

et al. 2009

View full text Add to dashboard Cite

1OBJECTIVE-Obesity and diabetes are characterized by the incapacity to use fat as fuel. We hypothesized that this reduced fat oxidation is secondary to a sedentary lifestyle. RESEARCH DESIGN AND METHODS-We investigated the effect of a 2-month bed rest on the dietary oleate and palmitate trafficking in lean women (control group, n ϭ 8) and the effect of concomitant resistance/aerobic exercise training as a countermeasure (exercise group, n ϭ 8). Trafficking of stable isotope-labeled dietary fats was combined with muscle gene expression and magnetic resonance imaging-derived muscle fat content analyses. 31 ]palmitate oxidation by Ϫ8.2 Ϯ 4.9% (P Ͻ 0.0001). Despite a decreased spontaneous energy intake and a reduction of 1.9 Ϯ 0.3 kg (P ϭ 0.001) in fat mass, exercise training did not mitigate these alterations but partially maintained fat-free mass, insulin sensitivity, and total lipid oxidation in fasting and fed states. In both groups, muscle fat content increased by 2.7% after bed rest and negatively correlated with the reduction in [d 31 ]palmitate oxidation (r 2 ϭ 0.48, P ϭ 0.003). I n our search of the environmental factors that fuelled the pandemic of obesity, we face a paradox. Although sedentary lifestyle has been highlighted for decades as one of the main factors triggering weight gain, the physiology of physical inactivity has received little attention (1). Clearly, the causal relationships between sedentary behaviors and obesity are essentially based on epidemiological studies or on the indirect beneficial effects of exercise training (2). None of these studies provide evidence to support a cause-and-effect relationship. RESULTS-In CONCLUSIONS-WhileObesity is a fat storage disease characterized by insulin resistance and a decreased capacity to oxidize lipids (3) in fasting (4) and postprandial (5) conditions. Because weight reduction was not associated with improvement in fat utilization (6), it was suggested as a primary impairment in the etiology of obesity, rather than an adaptive response. Consequently, the delineation of the causes responsible for this reduced capacity to oxidize fat appears to be a fundamental prerequisite to develop efficient strategies against obesity.We previously extended the early Mayer hypothesis (7) and hypothesized that the decreased fat oxidation observed in obese and postobese subjects is due to the generalized adoption of sedentary behaviors (8). Using strict bed rest as a model, we showed that physical inactivity, per se (i.e., independent of the known physical inactivity-induced energy balance changes), lowers fasting and postprandial fat oxidation (9). Unexpectedly, whereas monounsaturated dietary fat (oleate) oxidation remained unaffected by bed rest, saturated fat (palmitate) oxidation decreased by 11% (9). These results are interesting when considering the north/south gradient in obesity prevalence in France that was not associated with the overall energy intake but in the greater amount of saturated fat in the diet (10).The main objective of our present study wa...

show abstract

“…presence of muscular degeneration (fatty infiltration) in the cervical extensor muscles of individuals with persistent whiplash. 10,13 Larger amounts of fatty infiltrate were present in all of the cervical extenlash injury, it is important that more objective and quantifiable measures to classify the condition are explored and developed. Recent studies have established an MRI measure to quantify the fusive properties of healthy and acutely injured human skeletal muscle tissue (eg, lower extremity muscles and lumbar erector spinae).…”

Section: Diffusion-weighted Magnetic Resonancementioning

confidence: 99%

Diffusion-Weighted MRI for the Healthy Cervical Multifidus: A Potential Method for Studying Neck Muscle Physiology Following Spinal Trauma

Elliott

Pedler

Beattie

et al. 2010

J Orthop Sports Phys Ther

View full text Add to dashboard Cite

Magnetic resonance imaging analysis of the upper cervical spine extensor musculature in an asymptomatic cohort: an index of fat within muscle

Cited by 55 publications

References 18 publications

Association of Cross-Sectional Area of the Rectus Capitis Posterior Minor Muscle with Active Trigger Points in Chronic Tension-Type Headache

Association of Cross-Sectional Area of the Rectus Capitis Posterior Minor Muscle with Active Trigger Points in Chronic Tension-Type Headache

Physical Inactivity Differentially Alters Dietary Oleate and Palmitate Trafficking

Diffusion-Weighted MRI for the Healthy Cervical Multifidus: A Potential Method for Studying Neck Muscle Physiology Following Spinal Trauma

Contact Info

Product

Resources

About