Magnetic Nanoparticle Decorated N-Heterocyclic Carbene–Nickel Complex with Pendant Ferrocenyl Group for C–H Arylation of Benzoxazole

Naikwade, Altafhusen; Jagadale, Megha; Kale, Dolly; Gajare, Shivanand; Rashinkar, Gajanan

doi:10.1007/s10562-018-2514-1

Cited by 18 publications

(5 citation statements)

References 90 publications

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“…Undoubtedly, attempts to prepare suitably tailored NHC-metal complexes for explicitly targeting cancer cells can significantly contribute in target specific anticancer drug design and development program. [20,21] Considering aforementioned discussion and in continuation of our studies related to MNPs and biomedical applications, [22][23][24] we report herein in vitro anticancer, antibacterial and hyperthermia studies of a newly prepared caffeine functionalized N-heterocyclic carbene silver complex anchored on magnetic nanoparticles.…”

Section: Introductionmentioning

confidence: 88%

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Anticancer, Antibacterial and Hyperthermia Studies of a Caffeine‐Based N‐Heterocyclic Carbene Silver Complex Anchored on Magnetic Nanoparticles

et al. 2021

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Caffeine based N‐heterocyclic carbene (NHC)‐silver complex anchored on magnetic nanoparticles (MNP‐Caff‐NHC@Ag complex) has been prepared by covalent grafting of caffeine on the surface of chloro‐functionalized Fe3O4 magnetic nanoparticles followed by complexation with silver (I) acetate. The MNP‐Caff‐NHC@Ag complex has been characterized by Fourier transform infrared (FT‐IR) spectroscopy, energy‐dispersive X‐ray (EDX) spectroscopy, transmission electron microscopy (TEM), X‐ray diffraction (XRD), thermogravimetric analysis (TGA) and vibrating sample magnetometer (VSM) analysis. The MNP‐Caff‐NHC@Ag complex displayed significant in vitro anticancer activity against human hepatocarcinoma HepG2 cell line and antibacterial activity against Escherichia coli (NCIM‐2832), Staphylococcus aureus (NCIM‐2654) and Bacillus cereus (NCIM‐2703). The hyperthermia studies revealed that MNP‐Caff‐NHC@Ag complex achieved good therapeutic temperature (47 °C) under physiological safe range of field and frequency thereby forecasting potential applications as heating mediators in magnetic hyperthermia for selectively killing of cancer cells.

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Section: Introductionmentioning

confidence: 88%

“…Considering aforementioned discussion and in continuation of our studies related to MNPs and biomedical applications, [22–24] we report herein in vitro anticancer, antibacterial and hyperthermia studies of a newly prepared caffeine functionalized N ‐heterocyclic carbene silver complex anchored on magnetic nanoparticles.…”

Section: Introductionmentioning

confidence: 88%

Anticancer, Antibacterial and Hyperthermia Studies of a Caffeine‐Based N‐Heterocyclic Carbene Silver Complex Anchored on Magnetic Nanoparticles

et al. 2021

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“…The heat generated by the nano-magnetites is determined by the speci c absorption rate (SAR) and expressed in w g − 1 . SAR value of nano-magnetite (1), [Nano-magnetite-FemTriaz]Cl (6) and of nanomagnetite-FemTriaz-NHC-Au complex (7) were calculated by using the equation [33] The value of SAR depends on the size and concentration of particles, suspension medium, the magnitude and frequency of an external alternating magnetic eld. The magnetic induction hating is mainly caused by the hysteresis loss and residual loss in an AC magnetic eld.…”

Section: Magnetic Hyperthermia Studymentioning

confidence: 99%

Nano-magnetite supported N-heterocyclic carbene-gold complex with pendant ferrocenyl group as a multi-modal anti-breast cancer agent

et al. 2023

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A novel nano-magnetite supported N-heterocyclic carbenegold complex with pendant ferrocenyl group has been prepared by using a multi-step procedure. The complex displayed signi cantly higher anticancer activity against the MCF-7 breast cancer cell line with IC50 = 32.38 µg/mL as compared with standard drug 5-uorouracil (IC50 = 25.29 µg/mL) in the MTT assay. The in-ovo antiangiogenic activity of the complex using chicken chorioallantoic membrane assay showed signi cant decrease in secondary blood vessels indicating that it is e cient angiogenesis inhibitor. The hyperthermia studies of the complex revealed a signi cant speci c absorption rate (SAR) value of 246.974 Wg-1 with therapeutic temperature of 46.8 oC.

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“…In view of prior discussion and in continuance of our research associated with green chemistry, , in the present investigation, the advantages of materials that mentioned above are united. This study aims to establish a new heterogeneous ferrocene based Fenton system.…”

Section: Introductionmentioning

confidence: 98%

Photocatalytic Degradation of Methyl Orange by Magnetically Retrievable Supported Ionic Liquid Phase Photocatalyst

Naikwade¹,

Jagadale²,

Kale³

et al. 2020

ACS Omega

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A magnetically retrievable ferrocene appended supported ionic liquid phase (SILP) photocatalyst containing a molybdate anion has been synthesized and characterized by Fourier transform infrared, X-ray photoelectron spectroscopy, transmission electron microscopy, X-ray diffraction, energy dispersive spectroscopy, and vibrating sample magnetometer analysis. The optical properties of the photocatalyst were probed by photoluminescence and UV–vis diffuse reflectance spectroscopy. The discharge of undesirable dye effluents from textile industrial plants in the environment is the major concern of environmental pollution and toxicity. In this context, we employed the as-prepared SILP photocatalyst for degradation of methyl orange (MO) under UV light (365 nm) irradiation, and subsequently, recycling studies were performed. The histological alteration in gills of the fish is employed as a tool for monitoring toxins in the environment. In view of this, the histo-toxicological assessment on freshwater fish Tilapia mossambica gills asserted the damage of secondary gill lamellae due to MO. Conversely, structural modifications in the gill architecture were not observed by virtue of photodegraded products confirming that the degraded product is nontoxic in nature. Additionally, the normal behavior of fishes on exposure to photodegraded products reveals that research findings are beneficial for the aquatic ecosystem.

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Magnetic Nanoparticle Decorated N-Heterocyclic Carbene–Nickel Complex with Pendant Ferrocenyl Group for C–H Arylation of Benzoxazole

Cited by 18 publications

References 90 publications

Anticancer, Antibacterial and Hyperthermia Studies of a Caffeine‐Based N‐Heterocyclic Carbene Silver Complex Anchored on Magnetic Nanoparticles

Anticancer, Antibacterial and Hyperthermia Studies of a Caffeine‐Based N‐Heterocyclic Carbene Silver Complex Anchored on Magnetic Nanoparticles

Nano-magnetite supported N-heterocyclic carbene-gold complex with pendant ferrocenyl group as a multi-modal anti-breast cancer agent

Photocatalytic Degradation of Methyl Orange by Magnetically Retrievable Supported Ionic Liquid Phase Photocatalyst

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