Magnetic molecularly imprinted polymers for the selective determination of cocaine by ion mobility spectrometry

Preparation and Applications of Chiral Polymeric Particles

“…CPPs with boronic acid functional groups on the surface were generated. As reported, [64] boronic acid functional groups can specifically recognize structure with cis diol moiety due to the esterification reaction between boronic acid and cis diol. The resulting CPPs were used for chiral absorption and chirally controlled release towards chiral dopamine (Figure 9).…”

Sample Preparation Using Molecularly Imprinted Polymers

“…34,96,178 If most of the studies concern the trapping of a target molecule and one or two analogs in some cases, Li et al reported EFs from 16 to 20 for 6 NSAIDs in waste water with IFs between 2 and 2.3 using ibuprofen as template. 155 As for SPE-MIP, the validation of a dSPE procedure was mainly based on the intra-and interday studies of the extraction recoveries, measured mainly in pure media 59,96,180,184 but also in real samples, in their native form 62,181 or spiked at different concentration levels. 37,45,50,51,62,65,69,94,96,113,149,163,165,168,172,174,178,183,184 Li et al compared MIP and C18 silica particles to evaluate their difference in term of adsorption capacity of drugs from environmental waters, that was higher with the MIP (factor 2.6).…”

“…155 As for SPE-MIP, the validation of a dSPE procedure was mainly based on the intra-and interday studies of the extraction recoveries, measured mainly in pure media 59,96,180,184 but also in real samples, in their native form 62,181 or spiked at different concentration levels. 37,45,50,51,62,65,69,94,96,113,149,163,165,168,172,174,178,183,184 Analytical Chemistry Li et al compared MIP and C18 silica particles to evaluate their difference in term of adsorption capacity of drugs from environmental waters, that was higher with the MIP (factor 2.6). 155 A similar comparison was reported by Lu et al that observed a higher selectivity, with a better cleanup effect with the MIP.…”

“…58 As already reported for MIP-SPE, thanks to the cleanup effect brought by the MIP, chromatographic methods typically used to analyze the dSPE extract can be replaced by a direct analysis by IMS as it was done, for example, for cocaine in saliva, which is a faster but also greener method compared to LC−MS often used for this application. 184 The study of the reusability of the dSPE particles was often reported. The possibility to use them in 3, 53,105,185 5, 31,45,46,50,62,96,117,153,154,175,179,188 6, 43,94,94,111,113,167,172,182 7, 49,115 8, 37,44,102,159,180 9, 156 10, 35,47,163,170 20 178 and even 30 155 cycles was mainly studied in pure media and resulted in a difference in binding efficiency between 3 and 15% between the first and the last use.…”

Designing and controlling the morphology of spherical molecularly imprinted polymers

“…Therefore, it is very important to choose a suitable surface modifier. Armenta and co-workers 157 discussed the effect of the MNP modifier used on the extraction performance of M-MIPs. They employed PEG and 3-(trimethoxysilyl)propyl methacrylate(V) to modify MNPs prepared by a co-precipitation method, then coated MIPs by bulk polymerization.…”