Magnetic, Luminescent Eu‐Doped Mg–Al Layered Double Hydroxide and Its Intercalation for Ibuprofen

Abstract

A magnetic, luminescent Eu-doped Mg-Al layered double hydroxide with ibuprofen (IBU) intercalated in the gallery has been successfully prepared by a simple coprecipitation method. The physicochemical properties of the samples were well characterized by powder XRD, TEM, FTIR, TGA, inductively coupled plasma MS (ICP-MS), vibrating sample magnetometry (VSM), and fluorospectrophotometry. The results revealed that Fe(3)O(4) nanoparticles are coated on the surface of layered double hydroxides and the obtained (Mg(2)Al(0.95)Eu(0.05))(Fe)-(IBU) sample exhibits both superparamagnetic and luminescent properties, with a saturation magnetization value of 1.86 emu g(-1) and a strong emission band at 610 nm, respectively. Additionally, it was found that the ibuprofen loading amount is about 31 % (w/w), and the intercalated ibuprofen possesses sustained release behavior when the magnetic, luminescent composite is immersed in simulated body fluid (SBF).

Growth behavior of water dispersed MgAl layered double hydroxide nanosheets

“…26 The thickness of a brucite-like layer is ca. 0.48 nm, 34 and the d-spacing of the LDH sample was 0.87 nm. 26 Thus, LDH nanosheets were estimated to consist of 1-2 brucite-like layers.…”

Layered Double Hydroxide-Based Nanocarriers for Drug Delivery

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Development and characterization of size controlled polymeric microcapsules loaded with superparamagnetic nanoparticles

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