Magnetic field dependence of singlet oxygen generation by nanoporous silicon

Amonkosolpan, Jamaree; Aliev, G. N.; Wolverson, Daniel; Snow, Paul; Davies, J.

doi:10.1186/1556-276x-9-342

Cited by 7 publications

(10 citation statements)

References 13 publications

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“…In addition to microbubbles as the carriers for sonosensitizer molecules, inorganic nanosystems offers alternative and efficient platform for the loading of guest molecules such as sonosensitizers. On this background, silicon (Si) NPs were recently discovered as the efficient sonosensitizer for SDT . Typically, Si NPs were fabricated by a multistep electrochemical and high‐energy milling process ( Figure a) .…”

Section: Inorganic Micro/nanoparticle‐augmented Sonosensitizermentioning

confidence: 99%

Micro/Nanoparticle‐Augmented Sonodynamic Therapy (SDT): Breaking the Depth Shallow of Photoactivation

2016

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The fast development of photoactivation for cancer treatment provides an efficient photo-therapeutic strategy for cancer treatment, but traditional photodynamic or photothermal therapy suffers from the critical issue of low in vivo penetration depth of tissues. As a non-invasive therapeutic modality, sonodynamic therapy (SDT) can break the depth barrier of photoactivation because ultrasound has an intrinsically high tissue-penetration performance. Micro/nanoparticles can efficiently augment the SDT efficiency based on nanobiotechnology. The state-of-art of the representative achievements on micro/nanoparticle-enhanced SDT is summarized, and specific functions of micro/nanoparticles for SDT are discussed, from the different viewpoints of ultrasound medicine, material science and nanobiotechnology. Emphasis is put on the relationship of structure/composition-SDT performance of micro/nanoparticle-based sonosensitizers. Three types of micro/nanoparticle-augmented SDT are discussed, including organic and inorganic sonosensitizers and micro/nanoparticle-based but sonosensitizer-free strategies to enhance the SDT outcome. SDT-based synergistic cancer therapy augmented by micro/nanoparticles and their biosafety are also included. Some urgent critical issues and potential developments of micro/nanoparticle-augmented SDT for efficient cancer treatment are addressed. It is highly expected that micro/nanoparticle-augmented SDT will be quickly developed as a new and efficient therapeutic modality which will find practical applications in cancer treatment. At the same time, fundamental disciplines regarding materials science, chemistry, medicine and nanotechnology will be advanced.

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Section: Inorganic Micro/nanoparticle‐augmented Sonosensitizermentioning

confidence: 99%

Micro/Nanoparticle‐Augmented Sonodynamic Therapy (SDT): Breaking the Depth Shallow of Photoactivation

2016

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“…Finally, we consider the dependence of the SiNP:O 2 PL spectra on magnetic field at low T. We showed elsewhere that the PL recovers as the magnetic field lifts the spin degeneracies of the exciton and oxygen triplet levels and thereby suppresses the quenching by isolated O 2 due to triplet-triplet transfer. 26 This is evident in Fig. 3(a), which shows that the PL recovers dramatically in intensity as the magnetic field increases from zero to 6 T; this magnetic field dependence establishes that the donor state for energy transfer to isolated O 2 is a triplet exciton, and implies that the same is true for the dimers.…”

mentioning

confidence: 69%

“…6 Details of the etching and resulting porosity are given elsewhere. 26 PL from the SiNPs was excited by a continuous wave (CW) solid state laser (B450 nm, power B0.5 mW over area B1 mm 2 ) and PL from 2O 2 was excited using a mode-locked Yb-doped fiber laser (B1064 nm, repetition rate 20 MHz, average CW power B2-3 W); PL was detected using a response-corrected spectrometer (Acton SpectroPro 2300i) and cooled CCD.…”

mentioning

confidence: 99%

Observation of oxygen dimers via energy transfer from silicon nanoparticles

Aliev

Amonkosolpan

Wolverson

2016

Phys. Chem. Chem. Phys.

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Energy transfer from photo-excited excitons confined in silicon nanoparticles to oxygen dimers adsorbed on the nanoparticle surfaces is studied as a function of temperature and magnetic field. Quenching features in the nanoparticle photoluminescence spectrum arise from energy transfer to the oxygen dimers with and without the emission of Si TO(Δ) phonons and, also, with and without the vibrational excitation of the dimers. The dependence of the quenching on magnetic field shows that energy transfer is fast when a dimer is present, allowing an estimate of the proportion of the nanoparticles with adsorbed dimers.

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“…Exchange coupling between SiNP excitons and the ground triplet level of oxygen (the Dexter mechanism [4]) is believed to be the dominant process. Monitoring SiNP photoluminescence (PL) has proved particularly useful in understanding this phenomenon [5][6][7][8]. In the presence of oxygen, ET will depopulate the SiNP exciton levels and hence reduce (quench) the PL.…”

Section: Introductionmentioning

confidence: 99%

Singlet oxygen generation by nanoporous silicon: photoluminescence dynamics in magnetic field

Aliev

Amonkosolpan²,

Wolverson³

2019

Nanotechnology

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Singlet oxygen generation in porous silicon (PSi) was investigated by a magneto-optical experiment. Photoluminescence (PL) quenching due to an energy transfer (ET) process mediated by an exchange interaction was monitored in the spectral range 1.4–2.5 eV and in a magnetic field of 0–6 Tesla at different levels of oxygen concentration and excitation pump power. When a magnetic field was applied, both PL recovery and, for magnetic fields below 2 Tesla and high concentrations of oxygen, an unusual additional pump power dependent quenching of the PL was observed. A rate equation model describing the behavior of PL from PSi with oxygen adsorbed at cryogenic temperatures in magnetic field was developed. The model has been expanded to cover the ET process as a function of the nanoparticle size.

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Magnetic field dependence of singlet oxygen generation by nanoporous silicon

Cited by 7 publications

References 13 publications

Micro/Nanoparticle‐Augmented Sonodynamic Therapy (SDT): Breaking the Depth Shallow of Photoactivation

Micro/Nanoparticle‐Augmented Sonodynamic Therapy (SDT): Breaking the Depth Shallow of Photoactivation

Observation of oxygen dimers via energy transfer from silicon nanoparticles

Singlet oxygen generation by nanoporous silicon: photoluminescence dynamics in magnetic field

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